Description overdue on 06/19/2014
- Latin name: Phthalazolum
- ATC code: A07AB02
- Active substance: Ftalilsulfatiazol (Phthalylsulfathiazole)
- Manufacturer: Irbitsky HFZ, Russia; Pharmstandard-Leksredstva, Russia; Dalkhimpharm, Russia; Biosynthesis, Russia; Biochemist, Russia; PAT Kyivmedpreparat, Ukraine.
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications ftalazol
- Contraindications
- Side effects
- Instructions for use ftalazol (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
Tablet contains ftalilsulfatiazol - 0, 5 g and adjuvants ( talc, potato starch, calcium stearate ).
Product form
White or yellow flat tablets chamfer risk of packing 10, 20, 30, 50, 1000, 1500, 2000, 5000 or 10000 pieces.
Pharmacological action
Antibacterial . anti-inflammatory Group sulfonamides .
Pharmacodynamics and pharmacokinetics
The antibacterial activity of the active ingredient, as well as all other sulfonamides It relates to the fact that the structure is similar to the drug para-aminobenzoic acid Directly involved in the synthesis of folic acid in a cage microbe . And the development and growth of harmful microorganisms, depends directly on the synthesis processes purine and pyrimidine bases via folic acid . Use of sufficiently large doses ftalilsulfatiazol It allows to eliminate germs, despite stocks PABA tissue, does not form a new more stable strains of microorganisms .
Also, the drug has anti-inflammatory action. It stimulates production of glucocorticosteroids It reduces the intensity of migration leukocytes .
Drug exhibits the greatest activity with respect to Pneumococcus . Meningococcus . Shigella dysenteriae . Streptococcus . Gonococcus . Staphylococcus . Pseudomonas aeruginosa . Proteus vulgaris . Escherichia coli .
Upon receipt of funds the largest concentration in the centers rectum (most in intestinal lumen ).
Indications ftalazol
From what helps Ftalazol?
- from diarrhea Caused by bacteria;
- from shigellosis ;
- from colitis and enterocolitis ;
- treatment of chronic dysentery in exacerbations;
- gastroenteritis .
From what has prescribed pills Ftalazol?
Indications for use may be ftalazol condition after bowel surgery .
Contraindications
- allergy on components within or sulfonamides ;
- kidney disease, chronic;
- liver disease, acute;
- pregnancy and lactation ;
- glomerulonephritis ;
- Graves's disease ;
- blood disease ;
- ileus .
Side effects
- you may experience allergies ;
- headache;
- anemia Propafenone;
- stomatitis, gastritis, nausea , Epigastric pain;
- education kidney stones .
Instructions for use ftalazol (method and dosage)
The dosage and duration of treatment should appoint a specialist, depending on the degree of sensitivity microflora intestine to sulfonamides.
According to the instructions on Ftalazol, the daily dose should not exceed 7 grams, single - 2 grams.
In acute disease course prescribed:
- 1-2 day - 2 tablets every 4 hours;
- 3-4 day - 2 tablets every 6 hours;
- 5-6 day - 2 tablets - every 8 hours.
Further treatment:
- 1-2 day - 2 tablets after 4 hours, at night - one (total - 10);
- 3-4 day - 8 tablets per day, with an interval of 4 hours except for the night time;
- Day 5 - 6 tablets every 4 hours.
How to take Ftalazol children?
For children, the daily dose produced a decrease to 0, 2 g per kg body weight (children under 3 years old) to 0, 4 0, 8 g per kg of body weight (over 6 years). The drug is distributed into equal parts, sleep is not disturbed. The treatment usually is one week.
Overdose
You may experience macrocytosis and pancytopenia, increased side effects. This does not happen if parallel receiving medications administered folic acid.
Treatment is carried out according to exhibited symptoms.
Cooperation
Do not combine with acids, hexamethylenetetramine, adrenaline and kislotoreagiruyuschimi means .
At simultaneous reception with ftalazol oxacillin , The effectiveness of the latter decreases.
When combined with levomitsitin, nitrofurans and thioacetazone It increases the risk of side effects.
Barbiturates and para-aminosalicylic acid, antibiotics and others sulfonamides enhance the impact of the drug on the harmful microorganisms.
Combination with indirect anticoagulants It enhances the activity of the latter.
Terms of sale
It requires a prescription.
Storage conditions
In the reach of children, dark, cool place.
Shelf life
4 years.
During pregnancy and lactation
The drug is well and rapidly overcomes blood-placenta barrier Is found in breast milk and negatively affects the health of the fetus or child. Therefore, the drug during pregnancy and breast-feeding is not indicated.
Reviews ftalazol
Reviews of the good use of the drug. The drug quickly cope with diarrhea Is available. Another of the advantages of low cost, and noted security means, it can be given to children. Ftalazol is in any medicine cabinet and is very often used as a means of emergency.
Price ftalazol (Where to buy)
The price for 10 tablets of the drug is only 20 rubles.