Description overdue on 08/18/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications Motilak
• Contraindications
• Side effects
• Instructions for use Motilak (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

One coated tablet   It contains 10 mg domperidone   and optional ingredients: aerosil, lactose, carboxymethylstarch sodium, PVP, microcrystalline cellulose, starch, silicon dioxide, polysorbate 80, titanium dioxide.

One lozenges   contains 10 mg domperidone   and optional ingredients: magnesium stearate, advantoza FS-95, glucose, starch, carboxymethyl starch and flavor (natural peppermint oil).

Product form

The drug is available in tablet form: lozenges and tablets covered with a special coating. In each carton pack is 30 tablets (3 blisters of 10 pieces).

Pharmacological action

The structure of the active component domperidone   similar to neuroleptics And performance comparable to metoclopramide . The active substance has almost no effect on the expression gastric secretion   and can cause extrapyramidal disorder .

By increasing the time of contraction of the walls of the stomach and duodenum, the medication has a positive effect on peristalsis   gastrointestinal tract. The drug accelerates gastric emptying delaying bolus.

With reinforced gastroesophageal sphincter tone is achieved antiemetic effect .

Pharmacodynamics and pharmacokinetics

The active substance after oral administration is absorbed rapidly. The bioavailability of about 15% (low). At low acidity of gastric juice is reduced absorption of the active ingredient. Peak concentrations recorded after 60 minutes. Link to plasma proteins is 93%.

The drug penetrates into all tissues of the body, a small concentration recorded in the brain. In the liver, the intestinal wall is subjected to intensive medicine metabolism . The half-life - 7-9 hours.

Indications Motilak

From what drug Motilak? The drug is indicated for active:

• reflux esophagitis ;
• belching ;
• heartburn .

From what tablets domperidone   can be assigned:

• increased flatulence ;
• epigastric pain .

Indications for use in patients with Parkinson's disease : nausea   while taking Levodopa and Bromocriptine .

Contraindications

The drug is not prescribed for:

• bleeding in the digestive tract;
• individual hypersensitivity to derivatives domperidone ;
• mechanical obstruction of the digestive tract;
• perforation in the digestive system;
• diagnosis prolaktinomy .

Side effects

• skin rashes;
• gynecomastia ;
• extrapyramidal disorder (pediatrics);
• intestinal cramps;
• anaphylaxis ;
• hives .

Instructions for use Motilak (method and dosage)

How to administer Motilak?

Instructions for use: daily dose - 30 mg; single - 10 mg. The drug is recommended to be taken 30 minutes before meals. Lozenge should be kept in the mouth until dissolved; coated tablets can not crush, chew, and to share. In individual cases, the daily amount of medication may be increased to 60 mg.

Babies   (weight 20-30kg) appoint ½ tablets 2 times a day. Weighing more than 30 kg appoint 1 tablet twice a day.

Overdose

Enroll extrapyramidal disorder , Increased drowsiness , Disorientation in time and space. It is recommended that the appointment of enterosorbents   ( Activated carbon ), Early gastric lavage, the appointment of posindromnoy therapy.

Antihistamine medications   helping to stop extrapyramidal disorders.

Cooperation

Antisecretory agents   and antacids   can adversely affect the bioavailability Motilak.

M-holinoblokatory   reduce the ability of the medicament against the evacuation of the stomach and intestines.

HIV protease inhibitors, nefazodone . macrolides   and azole drugs increase the level of domperidone in blood.

Terms of sale

OTC Product.

Storage conditions

Protect from moisture. Temperature conditions recommended by the manufacturer - no more than 25 degrees.

Shelf life

2 years.

Cautions

If necessary, concurrent therapy antacids is recommended to maintain a 30-minute interval between doses of medication.

What is the best Motilium or Motilak?

The unequivocal answer is no. The active component acts in the formulations domperidone The only difference in producing medicines.

Analogs Motilak (structural substitutes)

Motinorm . Motoriks . Peridon . Motorikum . Motilak analogues produced in Russia and abroad.

During pregnancy and lactation

With care, providing for potential risks.

Reviews Motilak (overview)

The drug was well tolerated and effectively cope with belch . heartburn . swelling .

Reviews Motilak in pediatrics: fast action allows the drug in a timely manner to stop attacks epigastric pain   children.

Price Motilak where to buy

The cost of the package with 10 tablets is about 80 rubles. Price Motilak 30 tablets - 180 rubles.