Description overdue on 04/14/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications Trimedata (spectrum use)
• Contraindications
• Side effects
• Instructions on Trimedat (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• With alcohol
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

1 tablet contains 100 mg or 200 mg maleate trimebutin   and auxiliary substances: corn starch, colloidal silica, lactose, talc, magnesium stearate.

Product form

The drug is available in tablet form, in a package of 10, 20, 30 pieces.

Pharmacological action

Myotropic antispasmodic That regulates motility   Digestive System . Active substance affects enkephalinergic intestinal system governs peristalsis . Trimebutin has antispasmodic effect in hyperkinesis smooth muscle of the digestive tract, and in hypokinetic conditions stimulates the bowel.

The drug increases peristalsis and promotes emptying stomach , Reduces pressure on esophageal sphincter Acts throughout the intestines enhances smooth muscle response to various colon food stimuli.

With diseases of the digestive tract Associated with dysmotility, trimebutin helps to restore the physiological activity of the intestine.

Pharmacodynamics and pharmacokinetics

After entering into the tablet rapidly absorbed in the digestive system, ensuring maximum concentration of the active substance in blood in 1-2 hours. The index of bioavailability   It is 4-6%. A small amount of the drug penetrates placenta . Biological transformation occurs in the liver hepatic system, and the metabolites are excreted primarily in the urine.

Indications Trimedata (spectrum use)

From what pills Trimedat:

• motility disorders in functional gastrointestinal pathology;
• gastroezofagealnoreflyuksnaya disease;
• dyspeptic disorders when gastroduodenal disorders (vomiting, epigastric pain, nausea, disorders of digestion of food);
• paralytic ileus after surgery;
• irritable bowel syndrome, accompanied by pain, violation of the chair, cramps, colic;
• preparation for the survey of the digestive tract (endoscopic manipulation, X-ray examination).

Use of the drug in pediatric practice to successfully arrest dyspepsia in violation of GI motility.

Contraindications to the appointment of

Use of the drug is contraindicated in individual hypersensitivity to trimebutine. Tablets do not appoint in pediatrics before reaching the age of three.

Side effects Trimedata (Effects and reaction)

Abstract to the medicament contains information on isolated cases of side effects in the form of:

• violations of auditory perception ;
• changes in menstrual period;
• allergic responses;
• the emergence of anxiety.

Instructions on Trimedat (method and dosage)

How to take:   inside, not chewing and drinking water. Instructions for use Trimedata recommends a standard treatment regimen: three times a day for 100-200 mg. The maximum dose - 600 mg per day.

In order to prevent relapse syndrome Irritable bowel   drug prescribed to 300 mg per day. The drug can be taken for 4 months.

Instructions for use of tablets in pediatric patients: 25 mg three times a day for children 3-5 years. Children 5-12 years appoint 50 mg three times a day. How to take Trimedat: before or after meals? The medication with a meal is not connected.

Overdose

Cases of receiving large doses of trimebutine not described or recorded.

Cooperation

Application zotepine   It can lead to a lengthening anticholinergic effect . Registered increase in duration of action d-tubokurarina.

Terms of sale

Otpuskaetsya without prescription form.

Storage conditions

Away from the sun, away from children. Temperature range - up to 25 degrees Celsius.

Shelf life

The tablets can be stored up to 3 years.

Cautions

Embryotoxic and teratogenic effects   not identified. Alcohol has a significant negative impact on the course of treatment.

Analogs Trimedata (structural substitutes)

Trimebutin, Tribudat, Debridat, Neobutin. Price for analogs in Ukraine   is smaller than the original drug. For example, an analog Trimedata Tribudat can be bought for 40 UAH.

With alcohol

Invalid ethanol-reception drinks during treatment. Alcohol slows metabolic processes in the hepatic system, reducing the effectiveness of the medicament.

Trimedat during pregnancy (possibly use, reviews)

The decision to accept the appointment trimebutin only doctor. The drug is contraindicated in the first trimester. Reviews in pregnancy: Trimedat well relieves cramps and spasms in the digestive system without causing significant side effects.

Reviews on the Trimedat (General representation)

The drug was well tolerated, act quickly enough, eliminating the spasms, pain, stabilize the bowels. When constipation medication increases peristalsis, providing a quick, painless emptying of the colon.

Reception children, parents reviews: irritable bowel syndrome drug stabilizes motility, restoring the proper functioning of the digestive system.

Doctors about Trimedate: an effective, accessible the drug, widely used at a pathology of the digestive system.

Price Trimedat where to buy

The cost depends on the country, the region and the pharmacy network. The price of 200 mg pills in Russia: Novosibirsk - 147 rubles in St. Petersburg - 126 rubles, the price in Moscow - 120 rubles for 10 tablets. Buy in Ukraine may be at an average price 120grn (in the city of Kharkov - 125 UAH). How much is the medication in your area, please call the hotline pharmacy network.