Description overdue on 04/15/2014

  • Latin name: Macmiror Complex
  • ATC code: G01AH
  • Active substance: Nystatin, nifuratel
  • Manufacturer: DOPPEL FARMACEUTICI, S.R.L., Italy
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  • Composition
  • Product form
  • Pharmacological action
  • Pharmacodynamics and pharmacokinetics
  • Indications
  • Contraindications
  • Side effects
  • Instructions for use of candles and cream Makmiror complex (method and dosage)
  • Overdose
  • Cooperation
  • Storage conditions
  • Terms of sale
  • Shelf life
  • Cautions
  • Analogs
  • During pregnancy (and lactation)
  • Reviews
  • Price, where to buy

 Makmiror Complex

Composition

Vaginal Cream   It comprises:

  • Nystatin, nifuratel ;
  • glycerol , Sodium methyl parahydroxybenzoate, propylene glycol, triethanolamine, 30% ksalifin, propyl parahydroxybenzoate, sodium, sorbitol solution 70%, water.

Part vaginal suppositories   includes:

  • Nystatin, nifuratel ;
  • glycerol, titanium dioxide, sodium ethyl parahydroxybenzoate, gelatin, iron oxide yellow.

Product form

Pessaries   They are available in cartons containing a blister pack in which the suppository is 8 or 12 pieces.

Vaginal Cream   produced in the aluminum tube containing 30 g of cream. Included also is an applicator (a graduated syringe).

Pharmacological action

The means exerts antibacterial, antifungal and protivoprotozoynymi action of.

Pharmacodynamics and pharmacokinetics

Makmiror complex is a combined topical antifungal medication. Nifuratel effective against many types of bacteria, fungi and protozoa (eg, Trichomonas vaginalis ).

Nystatin is an antifungal antibiotic. It violates the permeability of the membrane of fungi, after which the cells are destroyed. Particularly effective against fungi Candida albicans .

The combination of nystatin and nifuratel allows you to increase the effectiveness of antifungal activity and expand the range of indications for use.

Makmikor complex of low toxicity, so it does not destroy the physiological flora, causes goiter and quickly restores normotsenoz vagina.

Indications

Complex treatment vulvovaginal infections That are caused by bacteria, fungi Candida, chlamydia and trichomonas.

Contraindications

Sensitivity to any component of the formulation.

Side effects

Very rarely allergic reactions - itch   and skin rash .

Instructions for use of candles and cream Makmiror complex (method and dosage)

The drug is used ingravaginalno .


Every day for 8 days before bedtime is applied via applicator 2, 5 g of cream. Instructions on candles Macromir complex is the same as for the ointment should be administered 1 suppository daily. To effect was maximal suppository inserted into the upper part of the vagina. After the treatment of menstruation can be repeated if necessary.

In childhood, vaginal suppositories does not apply in such cases it is recommended to use cream with applicator .

Overdose

Do not documented cases of overdose drug of.

Cooperation

Significant effect of the drug with other drugs have not been established.

Storage conditions

Drug should be stored at a temperature not exceeding 25 ° C, in a dark place.

Terms of sale

In drugstores the drug is sold on prescription.

Shelf life

3 years.

Cautions

At the same time should undertake treatment of sexual partner, using the cream for men to avoid the risk of re-infected. From sexual contact should be avoided during treatment.

Long-term use of the drug may cause hypersensitivity reactions.

It is necessary to stop the use of the drug in the event of allergic reactions .

Analogs

Analogs of candles Makmiror Complex: Betadine . Hexicon . yodoksid . osarbon . povidine .

During pregnancy and lactation

Do not use ointment and suppositories during pregnancy. During therapy should be stopped breast-feeding.

Reviews on the Makmiror The complex

Average rating means is 4, 75 points out of 5.

Reviews candlelight Makmiror complex and positive about a cream, all patients reported ease of use, no smell, the effectiveness and speed of action means. Among the disadvantages are the unpleasant yellow suppositories and cost.

You can find reviews Makmiror complex in pregnancy, despite the fact that its use in this case is not recommended.

Price Makmiror Complex

Cream in Russia is 465 rubles., In Ukraine - 172 UAH.

The price of candles Makmiror complex in Russia on average 491 rubles., In Ukraine - 109 UAH.

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