Description overdue on 11.10.2011

The main active ingredient - purified human menopausal gonadotropin . Menopur contains luteinizing hormone   (PM) and follicle-stimulating hormone   (FSH). The drug effectively used for women's and men infertility , Has gonadotropic effects. The basic material is prepared from female urine during menopause . According to the effects of drugs in women increases the concentration of hormones estrogen , Growth, maturation follicles . At persons male sex the drug activates the spermatogenesis , Products Testosterone . FSH reaches its maximum after 6-24ch after intramuscular injection of drugs, after which the concentration of FSH gradually falls. Half-life time - up to 12 hours.

Dosage Form:

Menopur is issued in the form of lyophilisate   for solution. Enter intramuscularly (allowed subcutaneous administration).

Indications:

In women, the drug is used for infertility caused by various disorders in the hypothalamic-pituitary the System . Also, drugs used for the purpose of conception, during events and other reproductive technologies. Men drugs prescribed for oligoastenospermii . azoospermia Caused by secondary hypogonadotropic hypogonadism   (jointly used HCG - human chorionic gonadotropin).

Contraindications:

Women: ovarian cyst   (other than polycystic ovarian syndrome), a persistent increase in the size of the ovaries, various types of anomalies and variations of genitalia, miomaticheskie nodes in the uterus incompatible with childbearing, vaginal bleeding   (for unknown reasons), tumors of the ovaries, uterus, mammary cancer , Pregnancy, primary insufficiency of ovarian, lactation. Men: androgen-dependent tumors, including prostate cancer .

Side effect:

GI : Diarrheal disorders.

Genito-urinary system Syndrome of increased stimulation of the ovaries (pain in the abdomen, dyspepsia , Weight gain, increase the number of red blood cells, ascites . electrolyte imbalance . pleurorrhea . hemoperitoneum . thromboembolism ), The formation and growth of cysts in the ovaries.

Endocrine system : A sharp increase estrogen excretion   excretion mastalgia , Uncomplicated moderately marked increase in the size of ovarian cyst formation. Men may develop gynecomastia .

At the site of injection drugs : Swelling, pain, hyperemia , A burning sensation.

Oliguria , Multiple pregnancy, weight gain, drop in blood pressure, allergies.

Route of administration:

Menopur administered subcutaneously or intramuscularly. Female infertility (when the hypothalamic-pituitary unbalance): initial dose 1-2 amp. (75-150 IU). If the ovaries do not respond, then increase the dose until the growth of the follicles, start to increase the concentration of estrogen. To induce ovulation after administration of the drug once administered 5-10 thousand. IU. Men for stimulating spermatogenesis hCG administered three times a week for 1-3 thousand. IU, then, after the normalization of serum testosterone for several months in an amount administered Menopur 75-150ME three times a week.

Special instructions:

Before treatment is necessary to spermoanaliz sexual partner . The woman should be assessed and gynecologist. As a result, the treatment of a high probability of multiple pregnancy.

Drug Interactions:

The drug can be combined with horagonom   (human chorionic gonadotropin) in women to induce ovulation after a stimulating effect on the growth of the follicle, the representatives of the male - to stimulate spermatogenesis.