Description overdue on 09/19/2013

Antifungal agent . It has a wide range of effects. The active substance is a derivative of benzothiophene and imidazole. The therapeutic dosage of the drug have fungicidal and fungistatic effects against dermatophytes, most pathogenic fungi (Candida tropicalis, Candida albicans, Candida spp, Pityrosporum orbicale) and other infectious agents mucous walls and skin (gram-positive strains of streptococci and staphylococci). The mechanism of action of the active ingredient sertaconazole   It based on the reduction of the output of the main membrane sterol of yeast and fungi -   ergosterol . Active substance increases the permeability of the cell membrane, leading to inevitable death, lysis of the fungus. Zalain available as ointments (cream), suppositories.

Indications:

Candles Zalain indicated for the treatment of fungal infections of the mucous walls of the vagina (vulvovaginal candidiasis). High efficiency is observed medicament for the treatment of diseases caused by staphylococci, streptococci , Fungi Candida and dermatophytes. Ointment Zalain actively used in the treatment of cutaneous fungal diseases: epidermomycosis , Colorful versicolor, candidiasis, tinea hands, feet, beards, body shin.

Contraindications:

Cream Zalain not prescribed for the individual hypersensitivity to the active component of sertaconazole and its derivatives. The drug is not recommended for use in pediatric patients due to the lack of evidence the effectiveness in children and severity of side effects. Zalain during pregnancy is contraindicated. Reliable data on the safety of sertaconazole in lactating and pregnant women do not have, but given the lack of systemic absorption of medication, as well as its single intravaginal administration is possible with use of the drug outweigh the potential benefit to the mother versus the possible risk to the unborn child.

Side effects:

Zalain cream may cause erythema development in the area of ​​application of the drug that does not require drug withdrawal. In some cases, treatment with diagnosed contact dermatitis. Candles from yeast Zalain may cause short-term itching and burning sensation in the vagina (the symptoms disappear at the end of antifungal therapy). The above side effects show the effectiveness of sertaconazole, and are frequently observed in the treatment of the local impact of drugs. Overdose drug is unlikely, given the method of application. If you accidentally medications inside appoint symptomatic treatment is recommended.

Mode of application:

The cream is applied in a thin, even layer twice a day for the entire area of ​​fungal infections of the skin, capturing 1 centimeter of surface area healthy. The average duration of therapy was 4 weeks and varies depending on the location and etiology of the infectious agent. Zalain from yeast administered in the form of suppositories: administered once, vaginally. Before using candles Zalain require mandatory toilet vulva, using an alkaline, neutral soap. Recommended time of administration - for the night. Tactics administration: lying on his back, deep into the vagina using a special applicator. In the absence of positive dynamics after the application of candles Zalain may re-introduction of one suppository a week.

Special instructions:

Analogs of the drug Zalain: Sertaconazole, Amiklon (Match pharmaceutical group). Instructions for use of the drug recommends Zalain stop breastfeeding at the time of antifungal therapy. It is unacceptable applying cream on the breast during lactation. Given the increase in breeding fungus Candida in the acidic medium, it is not recommended to use a variety of detergents, acidic agents after applying the cream. Medicament is not used in ophthalmic practice. In identifying fungi genus Candida on the mucous walls of the vagina, but in the absence of clinical symptoms, medication is not prescribed. Upon confirmation of candidiasis recommended to make every effort to identify and address the factors conducive to the emergence and development of the fungal infection. With Vulvovaginal candidiasis   with damage to the surrounding areas must simultaneously use and cream (externally) and suppositories (vaginally). During treatment requires total abstinence from sexual intercourse. Prevention urogenital reinfection   achieved by simultaneous treatment of sexual partner. Candles Zalain can be used during menstruation. The drug has no effect on the concentration, fast reaction rates, the ability to operate a motor vehicle. Responses to the drug Zalain indicate a good tolerability of sertaconazole and its high efficacy in the treatment of fungal infections of the skin and vulvovaginal candidiasis (in compliance with all the requirements and recommendations of the attending doctor).

Drug Interactions:

Candles Zalain may reduce the effectiveness of Local contraceptives   in their simultaneous application.