Description overdue on 11.01.2012

The anti-inflammatory drug for topical application, in the part Betamethasone   and salicylic acid . One gram of ointment contains 0, 5 mg betamethasone and 30 mg of salicylic acid. Betamethasone - a drug from the group corticosteroids , Anti-inflammatory, antipruritic and desensitizing effect. It affects the permeability of cell membranes and activates reuptake mast cells   mediators of inflammation, reduces the lesion tropism for blood cells responsible for the development of inflammation ( neutrophils and macrophages ) Influences the concentration cytokines and leukotrienes It inhibits the synthesis of interleukins . Salicylic acid enhances the permeability of the skin and improves the bioavailability of betamethasone, she also has an antibacterial action and, moreover, contributes to the restoration of physiological acidic environment of the skin. Diprosalik available as ointment 3%, 2% solution is evenly distributed on the skin surface has a cooling effect, has no effect on the hair (not dry out, does not stick together).

Indications:

Diprosalik actively used in dermatological practice for the treatment of kortikosteroidochuvstvitelnyh skin lesions of various etiologies. Prescribed for the treatment of psoriasis, atopic dermatitis, chronic (in this pathology disrupted nervous system that leads to the formation of small eruptions on the face, neck, and also in the area of ​​the genital organs and the anus); neurodermatitis (skin pathology caused by disruption of the central nervous system); in the treatment of flat lichen, eczema   (a skin disease of unknown etiology, the development of which are essential processes of the nervous and humoral regulation, characterized by inflammation of the moist), including eczema and nummular eczematous dermatitis, while pompholyx   (pathology of the sweat glands, which are formed when small itchy blisters) seborrheic dermatitis   (inflammation of the skin caused by disorders of the sebaceous glands); at about byknovennom ichthyosis   ichthyotic and other lesions. Diprosalik lotion designed specifically for use in the field of scalp diseases such as psoriasis, seborrheic eczema .

Contraindications:

Betamethasone dipropionate, like all corticosteroids, is contraindicated in skin lesions mycotic (fungal) etiology, as well as a patient TB . Contraindication to Diprosalik ointment is also the presence of the patient's history of hypersensitivity reactions to the drug or other corticosteroids.

Side effect:

It is possible the development of local effects, burning, itching, irritation, dry skin . Can join folliculitis   (inflammation of the hair follicles), in some cases there   hypertrichosis   (abundant growths of hair which is not peculiar to either sex or age). The treatment may appear ugrevidnye Diprosalik rash, hypopigmentation   (reduction of melanin in the skin and skin lightening). When applied to the solid dressings may develop Diprosalik reaction maceration and skin layer in the case of secondary infection. From the use of betamethasone on the skin may appear striae   (white stripes on the abdomen, in the area of ​​breast and thighs). The cause of stretch marks - atrophic processes that occur in the tissues of the skin under the influence of glucocorticoids.

Mode of application:

Diprosalik apply ointment topically applied to the skin altered, the procedure is recommended to repeat twice a day, the drug should be rubbed in a circular motion. Basic differences in the method of applying the lotion not enough time for one two or three drops Diprosalik lotion.

Special instructions:

Diprosalik is not intended for use in ophthalmic practice, and when it gets into the eyes, they should be thoroughly rinsed. Similarly come in contact with ointment Diprosalik mucous membranes. In pediatrics Diprosalik may be used, since two years. In pediatric patients are more likely than adults can watch the systemic side effects of treatment with corticosteroids - the oppression of their own adrenal development Cushing   and Cushing's syndrome , Slower growth is not an appropriate time limit weight gain. In the treatment of pregnant women should follow the principle of "do no harm", ie it is necessary to compare the potential benefits from the use of betamethasone dipropionate and a hypothetical risk posed corticosteroids for the future baby. Research in this area was conducted. If the treatment is accompanied by the development Diprosalik hypersensitivity   to the active substance and there is a tendency to develop allergic reactions, it is desirable to suspend the drug. If during treatment with corticosteroids is now a secondary infection, it should be treated with antibacterial drugs. After prolonged use of the drug therapy is stopped Diprosalik, gradually reducing the dose.

Drug Interactions:

As to the ointment and lotion Diprosalik include salicylic acid in combination with a corticosteroid, consider the following. Acid modifies the effect of drugs such as heparin, tolbutamide . Methotrexate . A similar effect was observed with respect to the group urikozuretikov . anticoagulants . For this reason, co-administration with Diprosalik above mentioned drugs may require adjustment of dose.