Description overdue on 27.12.2011

Glucocorticosteroid . It has a pronounced anti-allergic and anti-inflammatory action. Mainly active substance hydrocortisone acts. The mechanism of action is based on inhibition of release Cytokine   ( interleukins   and interferon) from the system lymphocytes   and macrophages, contributes significantly oppressed release of eosinophilic inflammation mediators current, greatly reduces the internal tsikloksigenazny or lipoxygenase metabolism, as well as the synthesis of prostaglandin . Stimulating existing steroid receptors in the patient's body to induce formation of internal protein lipokortina . Significantly reduces the inflammatory cell infiltration, as well as reduces the migration of leukocytes and lymphocytes   in the inner region of the inflamed organ. In the appointment of a physician at the recommended doses Lokoid potentially causing deliberate suppression of the hypothalamic / pituitary / adrenal axis. Available in the form of ointments, creams.

Indications:

Lokoid prescribed for a simple eczema , Simple and allergic dermatitis, atopic dermatitis, acquired atopic dermatitis. The drug is effective in erythroderma , Psoriasis, urticaria occurs itchy papules ( prurigo ), Outer lichen planus , Anogenital itching, inflammation of a variety of insect bites, progressing   photodermatosis .

Contraindications:

Lokoid not appoint postvaktsionalnom period, with pyoderma , Mycosis, skin diseases, viral, bacterial, fungal origin. The drug is contraindicated in cancerous skin lesions, syphilis , Ulcers, wounds on the skin. Do not use in pediatrics, breastfeeding, pregnancy. Ointment should not be applied to persons with perioral dermatitis with acne vulgaris , Rosacea.

Side effect:

Local irritation. Side-effects increase with prolonged use povyazkok occlusal and / or an extended surface, in the presence of systemic side effects

Mode of application:

Lokoid applied topically. The affected areas of the skin should be lubricated with a thin layer of ointment is not more than 4 times a day. Effective drug treatment Lokoid lasts from 1 to 3 weeks. A certain dose of the drug used for seven days, the dose should not exceed 30-60 g In the presence of itching in the anus of the patient prior to applying the drug should wash the anal area with warm water using a toilet or laundry soap, then rinse with warm, running water and thoroughly dry the damaged surface of the skin with a towel or paper towel.

Special indications:

Avoid ointment in the eye .  It is strictly prohibited for children under 12 years of age to apply ointment Lokoid without medical supervision .  If within seven days the use of the drug prescribed by the doctor "Lokoid ointment" significant improvement does not occur or there is a clear deterioration of the patient, as well as the presence of symptoms prior to renewal after a certain period after its cancellation, the use of this drug should definitely stop .  Strongly Lokoid not be used without first consulting with your doctor, especially when not passing itching in the genital area of ​​women, the patient is accompanied by a specific vaginal discharge .  With a fairly long-term treatment and / or applied to much larger areas are encouraged to designate food restricted diet products containing sodium and increase the number of products containing K +; The most effective is the introduction into the patient a sufficient amount of protein .  It requires regular control of blood pressure, blood glucose, and the content Cortisol   in the patient's blood. It is necessary to control blood clotting index diuresis As well as the body weight of the patient.