Description overdue on 10/12/2014

  • Latin name: Testosterone Propionate
  • ATC code: G03VA03
  • Active substance: Testosterone (Testosterone)
  • Manufacturer: "Farmak"
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  • Composition
  • Product form
  • Pharmacological action
  • Pharmacokinetics and pharmacodynamics
  • Indications
  • Contraindications
  • Side effects
  • Instructions for use (method and dosage)
  • Overdose
  • Cooperation
  • Terms of sale
  • Storage conditions
  • Shelf life
  • Cautions
  • Analogs
  • Babies
  • During pregnancy (and lactation)
  • Reviews
  • Price, where to buy

 Testosterone Propianat

Composition

The solution contains an active substance testosterone As well as an auxiliary ingredient ethyl oleate.

Product form

The solution is an oily liquid, which has bright yellow or green. The solution has a peculiar odor. Implemented testosterone in 1 ml ampoules in package of 10 vials fit. The oil solution can be 1% or 5%.

Pharmacological action

Wikipedia shows that the drug provides a pronounced anabolic and androgenic activity by regulating protein synthesis and function of the male reproductive glands.

Testosterone propionate   It has on the specific androgenic effects. His influence on the body provides the stimulation of development and function of the external genitalia, prostate, seminal vesicles, the secondary male sexual characteristics. Testosterone is involved in the formation of male sexual behavior, and is also involved in the construction of the constitution of the body, provides stimulation of spermatogenesis. Under the influence of testosterone production decreases lyuteotropnogo and follicle-stimulating hormone.

Hormone testosterone   - Antagonist is estrogen , Female hormones. It ensures the development of an antitumor effect in breast tumors in women. The substance provides an anabolic effect, whereby stimulated protein synthesis, decreasing the amount of fat in the body is delayed a number of elements which are necessary for protein synthesis. Under the influence of this hormone increases the degree of fixation of calcium in the bones, increases muscle mass.


If a person teaches sufficient protein diet, it stimulates the production of erythropoietin.

Pharmacokinetics and pharmacodynamics

After the subcutaneous or intramuscular administration of the substance is slowly absorbed from the place where it was introduced. Once in the bloodstream, testosterone gradually falls to the authorities, which is its reduction to 5-α-dihydrotestosterone interacting with the receptors of the cell membrane. Further, it penetrates into the nucleus of cells. In the blood plasma of 98% of testosterone is bound to proteins. Metabolism occurs in the liver metabolites are excreted through the kidneys. Another 6% of unchanged output through the intestines.

Indications

Prick testosterone shows men who celebrated sexual underdevelopment, functional disorders of the reproductive system of character, the period of menopause (in adulthood men), and related vascular diseases and nervous system. The drug is also indicated for prostate hypertrophy, acromegaly, eunuchoidism, Impotence Associated with endocrine disorders, in post-castration syndrome, oligospermia.

Women means shown in neurological and vascular disorders that are associated with a period menopause For the treatment of ovarian cancer and breast cancer (age for women to 60 years old). Testosterone is indicated for uterine bleeding dysfunctional nature of women in old age; at mastitis Which is accompanied by tension of the mammary glands in the premenstrual period; at uterine cancer . endometriosis .

Contraindications

Sportviki indicates that the means can not be used with the following diseases and conditions:

  • prostate cancer or breast in males;
  • Individual high sensitivity to the active ingredient;
  • prostatic hyperplasia ;
  • gynecomastia;
  • disorders of urination;
  • violation of the kidneys and liver;
  • heart failure;
  • myocardial infarction ;
  • hypercalcemia;
  • diabetes ;
  • swelling.

Do not held the administration of testosterone in patients with severe asthenia, men in old age, when women pregnancy   and breast-feeding .

Side effects Testosterone Propionate

During the treatment with testosterone, in particular upon receiving high doses it can be observed such side effects:

  • increased sexual arousal, frequent erections;
  • salt and water retention;
  • masculinization in women (facial hair and body hair, deepening voice);
  • pastoznost person (deterioration of elasticity, a small swelling and whitening facial skin);
  • atrophy of the breasts, breast pain.

If large doses of the drug to treat a woman takes dysmenorrhea , It can completely stop menstruation.

The boys and adolescents in the treatment agent may be too active puberty, increase sexual organs.

Moreover, possible side effects following expression:

  • apnea . respiratory disorders ;
  • tendency to thrombosis;
  • arthralgia, pain in the legs, cramps;
  • nausea, diarrhea, jaundice;
  • acne, itching, seborrhea;
  • weight gain;
  • from yl sweating, dizziness, nervousness, depression;
  • local reactions at the places where the drug was administered.

Instructions for use (method and dosage)

When receiving Testosterone propionate instructions for use should be carefully observed by the patient. Guide provides that solution 1% or 5% are administered to a patient by subcutaneous or intramuscular injection of 1 ml. The interval between injections - 1-2 day course of treatment lasts from two weeks to several months.

How to take Testosterone Propionate women determined by the physician depending on the disease and symptoms. With   dysfunctional bleeding from the uterus 1-2 ml of a 1% solution is administered over about one month.

With eunuchoidism . acromegaly . congenital underdevelopment sexual glands once in two days introduced 25-50 mg. The duration of therapy depends on its efficiency. Later, a maintenance dose - 5-10 mg a day.

With menopause in men And when   impotence endocrine origin is assigned to 10 mg of the drug every day or 25 mg 2-3 times a week. Treatment should last 2-3 months.

With   prostatic hypertrophy for 1-2 months, administered at 10 mg every other day.

As stabbing Testosterone propionate male infertility It determines specialist, taking into account individual characteristics of the organism.

Take the drug to healthy people to develop the muscles and increase endurance doctors do not recommend. However, with sports training and strong physical exertion, some trainers recommend a course of testosterone propionate solo or combination of this drug with other drugs. For example, a parallel course is appointed Winstrol . The drug Winstrol - an anabolic steroid. It is also possible joint courses testosterone preparations Turinabol . Stanozolol   and etc.

Overdose

If over time the drug is administered in high doses, may subsequently be side effects that are described above. In such a situation, the treatment should be stopped, it is possible to proceed only after the disappearance of symptoms related to androgen. It should be administered smaller doses of testosterone.

With an overdose of women possible cessation of menstruation.

Cooperation

Effect of Testosterone Propionate reduced if combine it with rifampicin, barbiturates, phenylbutazone, carbamazepine, phenytoin.

If the patient has a pronounced hypogonadism, Testosterone Propionate is recommended to be combined with Estrogen With agents that stimulate the thyroid function.

The drug enhances the effect of vitamins, anabolic drugs, drugs that are composed of phosphorus and calcium. Testosterone slows the elimination of cyclosporine.

Under the influence of androgens can be enhanced hypoglycemic effect of insulin, therefore, you may need a dose reduction hypoglycemic agents.

Possible effect on the metabolism of several drugs. Also, there is evidence that testosterone increases the activity of oral anticoagulants. Sometimes there is the need to reduce the dose of the latter.

At the same time taking testosterone and corticosteroids or adrenocorticotropic hormone increases the risk of edema.

Active testosterone is reduced while receiving alcohol and barbiturates.

Terms of sale

Over the counter medications can be purchased with a prescription.

Storage conditions

Protect from light LS from the reach of children. Storage temperature - between 15 to 25 degrees Celsius.

Shelf life

Keep the solution may be 2 years. It should be taken into account, how to store Farmak Testosterone correctly.

Cautions

With the introduction of the solution, it is important to make sure that he did not get into the vessels. To avoid local and general adverse reactions, it is necessary to introduce a means very slowly.

With testosterone treatment, be sure to monitor the status of the body of people suffering from hypertension, epilepsy , Kidney disease, migraine , Congestive heart failure.

Before you start the administration of the drug, it is necessary to conduct a survey and eliminate prostate cancer in men, as it increases the probability of prostate hyperplasia.

When testosterone treatment children can celebrate their rapid growth and too active bone maturation. There may also be premature to close the growth zone of the pineal gland.

Those patients, who for a long period of time to take this medication, it is necessary to control some laboratory parameters: testosterone concentration, hematocrit, hemoglobin And to carry out liver function tests.

Because of an increased tendency to form blood clots while taking this drug should be careful to take it after the recently conducted operations or trauma.

In the treatment agent is desirable to refrain from transport management, and perform other operations that require precision.

Analogs

Analogues of testosterone propionate are other medicines that contain testosterone. This medication Andriol . Nebido . Androzhel . Sinandron . Testoviron   and etc.

Babies

In the absence of data on the safety of this treatment, the drug is not recommended for use in the treatment of children.

During pregnancy and lactation

Since Testosterone Propionate may trigger the development of a teratogenic effect, means is contraindicated for the treatment of pregnant women   and lactating mothers . Especially dangerous is its reception in the first trimester of pregnancy.

Reviews of testosterone propionate

Reviews about this drug testify to its high efficiency. Patients notice improvement in many diseases, but it points to the need to pay attention to contraindications to the use of the solution. It should be clearly adhere to the regimen, which has appointed a specialist to get the desired effect.

Despite the recommendation not to use this tool to improve physical fitness, most of the reviews of testosterone propionate solo and combination with other drugs leave those who are actively involved in sports. It is noted that under its influence to actively increase muscle definition, increases muscle mass. However, the drug has a short duration. Most often it is combined with tools such as Turinabol, etc. Stanozolol.

Price Testosterone Propionate, where to buy

The price of the drug (5 vials) an average of 500 rubles. The easiest way to buy a vehicle, ordering it online. Buy Testosterone Propionate in a pharmacy in Ukraine can be as low as 80 USD for 5 ampoules.

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