Description overdue on 09/23/2014

  • Latin name: Ventolin
  • ATC code: R03AC02
  • Active substance: Salbutamol sulphate (Salbutamol sulaye)
  • Manufacturer: GlaxoSmithKline Trading (Russia)
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  • Composition
  • Product form
  • Pharmacological action
  • Pharmacodynamics and pharmacokinetics
  • Indications
  • Contraindications
  • Side effects
  • Instructions for use Ventolin (method and dosage)
  • Overdose
  • Cooperation
  • Terms of sale
  • Storage conditions
  • Shelf life
  • Analogs
  • Babies
  • Reviews
  • Price, where to buy

 Ventolin

Composition

The active substance of the preparation - salbutamol sulphate . In addition, it has a tetrafluoroethane   - 1 dose.

Product form

Pharmacies can be found Ventolin aerosol   (Ventolin inhaler). Moreover, Ventolin in Nebula is sold as solution for inhalation . Also, a medicine can be found in tablets   and a   Syrup .

Pharmacological action

Bronchodilator   means.

Pharmacodynamics and pharmacokinetics

The drug is used to prevent bronchospasm . It bronchodilator - Or rather, selective beta-2-agonists . It increases lung capacity and mucociliary clearance , Activates ciliated epithelium It improves mucus secretion, expands coronary arteries Reduces the potassium content, it acts as a hyperglycemic   and lipolytic agent It has an impact on glycogenolysis   and insulin secretion, increases the risk of acidosis .

The drug effect rather quickly, almost 5 minutes after application (maximum - after 30-90 minutes). Duration of effect - about 5 hours.

10-20% salbutamol after use are in the lower respiratory tract. These are absorbed in the lung tissue and blood, but is not split. The remaining amount of active substance is retained in an inhaler or in the oropharynx and then swallowed and actively split when passing through the liver, with the conversion into phenolic sulphate .


The degree of association with plasma proteins - about 10%.

Received salbutamol cleaved in blood for 72 hours in the liver and excreted primarily in the urine as phenolic sulphate   or unchanged. A small part is excreted in the feces.

Indications

The inhaler and a solution for him to apply to the Ventolin bronchitis   chronic form, asthma   and COPD   with reversible airways obstruction.

Contraindications

The drug should not be used in patients with chronic Heart Failure , Hypersensitivity to the components, pregnancy , Children younger than 18 months, breast-feeding .

Side effects

Generally, among the side effects noted tremor   finger Headache The appearance of anxiety. In addition, the following adverse reactions:

  • hypersensitivity as hives . hypotension . angioedema . bronchospasm . collapse ;
  • hyperactivity;
  • paradoxical bronchospasm ;
  • muscle cramps;
  • hypokalemia ;
  • lactic acidosis ;
  • tachycardia ;
  • heart palpitations;
  • expansion of peripheral vascular disease;
  • arrhythmia ;
  • arrythmia ;
  • supraventricular tachycardia ;
  • irritation of the mouth and throat.

Instructions for use Ventolin (method and dosage)

Instructions for use Ventolin warns that the drug should be used correctly, regardless of the form of release, or the healing process can go wrong.

In addition, be sure to take the medication only after consulting your doctor.

Instructions on Ventolin inhalation aerosol in the form of reports that for the use of the drug must be used nebulizer   with a mask and endotracheal tube .

Ventolin Nebula, which is sold in the form of a solution for the inhaler is used without dilution. The duration of inhalation - about 10 minutes. The medicine may be diluted with sterile sodium chloride solution (0, 9%). It should be used in well ventilated rooms, because a certain amount of product into the environment.

Instructions on Nebula Ventolin inhalation recommends a dose of 2, 5 mg. If necessary, it can be increased up to 5 mg. Frequency of use - 3-4 times a day. For adult patients, if necessary, in the hospital the dosage is increased to 40 mg per day.

Aerosol for inhalation suitable for approximately 200 times use. They can use the adult patients and children from 2 years after the appointment of an expert. With the purpose of long-term maintenance of therapy adults appoint typically 200 mcg up to 4 times a day. To prevent bronchospasm   childhood used 100-200 mg (1-2 inhalation).

Syrup is appointed by to patients in adulthood on 2 ml 3-4 times a day. If necessary, the dosage may be increased to 4 ml.

Overdose

At the use of the drug in doses in excess of the available hypokalemia . tachycardia , Nausea, decreased blood pressure, muscle tremors , Vomiting, agitation, respiratory alkalosis . headache . hyperglycemia . anoxemia . In rare cases appear hallucinations . tachyarrhythmia , Expansion of peripheral vascular spasms, ventricular flutter .

For treatment applied cardioselective beta-blockers But with caution, if at history   have seizures bronchospasm .

Cooperation

Ventolin inhalation should not be used in conjunction with non-selective beta-adrenergic receptors . Patients with thyrotoxicosis   the tool also enhances the effect of stimulants of the nervous system and tachycardia .

If you combine the aerosol and a solution for inhalation xanthines It increases the likelihood of tachyarrhythmia . FROM Levodopa   and means for inhalation anesthesia   increases the risk of severe ventricular arrhythmias . Together with anticholinergic   medicines may increase intraocular pressure. In the appointment of diuretics   and GCS   increases gipokaliemicheskoe effect .

Terms of sale

The drug is sold by prescription only.

Storage conditions

Keep the medication should be out of the reach of children and well-protected from light. His must not be frozen or apply heat to, the optimum temperature - no higher than 30 ° C.

Shelf life

The drug should be stored no longer than 2 years.

Analogs

Match code ATC 4th level:
  •  Ventolin
 Berotek
  •  Ventolin
 Foradil

Analogs of Ventolin and Nebula and Ventolin Ventolin Easy Breathing in pharmacies can get, as a rule, the following:

  • Ventilor ;
  • Nebutamol ;
  • Salamol Ster-Neb ;
  • Eco-salamol ;
  • Salamol Eco Easy Breath ;
  • Salbutamol ;
  • Salbutamol-Intel ;
  • Salbutamol Neo- .

All of them have different costs. In many cases, counterparts are less than the Ventolin.

Babies

Inhalation can be used for children relief   attacks bronchospasm   at a dosage of 100-200 mg (1-2 inhalation). Supportive therapy Ventolin - up to 200 micrograms 4 times a day (2 inhalations). For the prevention of use of the 100-200 mg 10-50 minutes before provoking factor (1-2 inhalation).

For children are used spacers «Bebihaler" or "Volyumatik».

The clinical effectiveness of this tool in children under 18 months using nebulizer   It was not investigated.

Reviews of Ventolin

Reviews of Nebula in the Ventolin, as well as aerosol found mostly positive. Patients say his performance. Few complain of side effects and addictive. However, for those interested, hormonal or not this drug, physicians are uniquely responsible that hormones and do not recommend to use it without any special purpose.

Price Ventolin where to buy

Price Ventolin inhalation at dosages of 100 mg - about 170 rubles. As a solution, the tool is more expensive. Price Ventolin Nebula - an average of 270 rubles. Ventolin Easy Breathing costs about 150 rubles.

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