Description overdue on 17.02.2012

Glucocorticosteroid . Active substance - fluticasone . Nazarel applied topically: intranasal and inhaled. The drug has anti-allergic and protivoootechnoe action. Nazarel able to restore the patient's response to the action bronchodilators That reduces the frequency of their use. The mechanism of drug action based on inhibition of proliferation lymphocytes Eosinophils,   mast cells Neutrophils, macrophages. The drug reduces the production, release of inflammatory mediators and bioactive substances (prostaglandins, cytokines, leukotrienes, histamine ). Nazarel available as a nasal spray with pump.

Indications and contraindications:

Nazarel effectively used for the treatment of allergic rhinitis (year-round seasonal flow variations). The drug is prescribed as a preventive allergic response to an allergen. Nazarel is contraindicated in case of intolerance to fluticasone.

Side effect:

Spray Nazarel can cause local adverse reactions: burning, irritation, dryness of mucous membranes of the nose and throat. There perversion of taste, odor, nasal congestion, nose bleed . Among the formidable, but redkovstrechaemyh side effects can be noted perforation of the nasal septum associated with surgical interventions in history. Use of the drug in Nazarel recommended dosage does not cause changes in the hypothalamic-pituitary, adrenal systems .

Mode of application:

Nazarel applies solely intranasally .  It is recommended to use the drug on a regular basis in order to achieve maximum therapeutic effect .  Spray is applied once a day, injected at 100 mg in the morning in each nostril .  The maximum permitted daily dose of fluticasone - no more 200mkg into each nasal passage .  The elderly do not require dosage adjustment .  Children 4-11 years of 50 mcg injected once daily into each nasal passage .  The maximum therapeutic effect is observed on the third day .  Before use, the bottle is shaken gently, index and middle fingers on either side of a tip of the thumb under the bottom of a spray put .  Before use, make sure of serviceability sprayer, this spray is directed away from you and cash in on the dispenser, OK should appear a small cloud of nebulized fluticasone .  Before injection must be carefully blow your nose to clear the nasal passages and .  When injected into one nostril, the second must be closed .  Tilt the head slightly forward, the vial should be positioned at the same vertical .  On the inhale do injection, exhale - through the mouth .  After using the spray tip is processed, cleaned from the remnants of the drug, close the special cap .  Once a week spray washed with warm water and dried in a warm place .  Keep away from heat, to avoid overheating, which can lead to deformation of the tip .  With a significant blockage of the tip, it is soaked in warm water, then washed and cleaned .  It is unacceptable cleaning tip with sharp objects, pins, etc. . P .

Special instructions:

Long-term use of the drug Nazarel requires constant control over the work adrenocortical . Against the background of allergic diseases may occur ophthalmic allergy symptoms, which requires the use of additional medication. Nazarel can be used for infection of the respiratory system. After systemic corticosteroids drug is prescribed with caution.