Description overdue on 25.01.2012

Oral contraceptive , Monophasic, combined. The preparation Rigevidon includes two active ingredients: ethinylestradiol   and levonorgestrel . Ethinyl estradiol - synthetic analogue Estradiol . Levonorgestrel is synthetic progesterone   (nortestosterone derivative) is superior in the expression of endogenous progesterone effects, which makes it possible to use the substance in minimal concentrations. One tablet of Rigevidon contains two active substances. White tablets in packing 21, they provide contraceptive effect . The content of ethinyl estradiol - 30 micrograms and levonorgestrel - 150 micrograms. Also in the package rigevidon addition of white tablets, contains seven tablets a reddish color. It iron preparation   (iron fumarate 76 mg), which is designed to restore iron stores in the body of a woman who loses it every month during menstruation. The mechanism of action is associated with Rigevidon hypothalamic structures   brain. Included in the drug levonorgestrel and ethinyl estradiol are a very good imitation of endogenous sex hormones women and subcortical structures are not able to notice the change. As a result, hypothalamus   assesses the level of sex hormones in the blood as high, and reduces the production factors (releasing factors) that are responsible for increasing the synthesis of sexual hormones. Without these factors, the pituitary refuses to produce the proper amount FSH and LH And without them, in turn, slows down and stops at all the process of follicular maturation. Ovulation   It does not occur, and therefore it becomes impossible to conceive. Among other effects of levonorgestrel is worth noting an increase in the density of the secretion of the cervix, which makes the task of sperm penetration into the uterus is almost impossible. The endometrium changes its structure, making it difficult to attach the ovum to the uterine wall. All of these effects are completely reversible, and after stopping the contraceptive female reproductive function fully restored within 2-3 months. Rigevidon is available in tablet form.

Indications:

Rigevidon prescribed to women of childbearing age in order to prevent unwanted pregnancies. However, the drug can also be used for other indications: rigevidon components have a normalizing effect on the level of sex hormones, which allows their use for various violations of the menstrual cycle: the irregular menstruation, when excessively painful menstruation, heavy bleeding when menstruating.

Contraindications:

Right important to note that Rigevidon is contraindicated in pregnancy. Before you start taking the drug a woman is obliged to undergo an examination by a gynecologist, which should exclude pregnancy. If the couple wants to have children, it is recommended to stop taking the drug for 3 months before the expected date of conception. Do not take Rigevidon when expressed violations of the liver system, including the gallstones and cholecystitis . If there is a history of the life of the transferred earlier hepatitis appointment rigevidon possible only after the determination of liver enzymes. Within six months after suffering a viral hepatitis is better to refrain from the use of Rigevidon. The drug is contraindicated in the presence of severe heart disease and blood vessels, including the history of cerebrovascular disease. Oncological diseases, severe hypertension, metabolic diseases, endocrine pathology, blood disorders ( anemia ) - All making use of these pathologies rigevidon impossible. In the presence of uterine bleeding of unknown origin have to postpone the decision to start taking the drug to ascertain the circumstances which caused the bleeding. Rigevidon is also contraindicated in heart attack, migraine, retinal thrombosis , Diplopia, with proptosis At thrombophlebitis , Thromboembolism, bleeding disorders in relatives.

Side effect:

Rigevidon is well tolerated, however, the likelihood of side effects still can not be excluded. From the digestive system Vomiting, indigestion, minor pain in the epigastric region. Central nervous system : Mild headache, mood lability, weakness and fatigue, irritability. In rare cases, may increase the occurrence of muscle excitability and seizures. Sexual function, too, can change that will be felt in the form increased libido Or in the form of a reduction of libido. Among other side effects is an opportunity to call coarsening of the mammary glands, rashes, bleeding between periods, skin pigmentation. As far as the issue of concern to all women on changes in body weight, here it is possible both increase and decrease. It is worth paying attention to another side effect of the drug: levonorgestrel changes vaginal secretion, against which can develop lesions of the mucous membrane of fungal origin.

Mode of application:

Starting with the need to use rigevidon white tablets in the first or the fifth day of the menstrual cycle. Their woman drinks daily, once daily, and preferably at the same time. If for some reason a pill white woman missed and the interval between doses was more than 36 hours, you should resort to additional methods of contraception, and the cycle of missed tablet simply deleted. At the end of 21 days of white pills run out, and the time comes to take the red. They should also drink once a day. If you skipped intake of red pills, do not be alarmed. They do not contain hormonal ingredients, and because their reception does not affect fertility. After 28 days of dosing cycle Rigevidon have to start anew, taking a break between the tablets should not be. If Rigevidon appointed for therapeutic purposes (after an abortion at menstrual disorders ), There are no fundamental differences in the regimen will not only pay attention to is the fact that after the abortion, hormonal drugs should be started on the day of surgery or the next. Taking medication should be accompanied by regular examination by a gynecologist at least twice a year.

Special instructions:

Precautions should approach the application rigevidon young girls in the absence of a regular cycle. Gently appoint patients with Rigevidon uterine myoma , from mastopathy . During lactation Rigevidon is not assigned as the active ingredients of the drug excreted in the mother, including breast milk. Mental illness ( epilepsy , Depression) is a relative contraindication to use Rigevidon, and in these cases should be with caution. This is also true with respect to diseases such as the tuberculosis , Varicose veins, multiple sclerosis . ulcerative colitis . In patients with liver disease, cardiovascular system, disorders of the hematopoietic function of course of taking Rigevidon should be accompanied by a regular (once in three - six months), laboratory and instrumental examination function of the affected organs. If there are signs of the emergence of insufficiency, receiving Rigevidon should be stopped. Drug overdose is practically impossible, but if for some reason it is casuistic yet occurred, you just need to stop taking Rigevidon, stomach wash and take sorbents.

Drug Interactions:

Many drugs that enhance the activity of the liver enzyme systems (antibiotics, tranquilizers , Dihydroergotamine, phenylbutazone) reduce the effectiveness of Rigevidon, in the case of simultaneous reception requires the use of additional methods of contraception. Himself Rigevidon improves anticoagulants , Beta-blockers, a number of antidepressants, can affect blood sugar levels. Patients with diabetes   you may need a dose adjustment of insulin.