Description overdue on 09/23/2014
- Latin name: Ventolin
- ATC code: R03AC02
- Active substance: Salbutamol sulphate (Salbutamol sulaye)
- Manufacturer: GlaxoSmithKline Trading (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use Ventolin (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- Babies
- Reviews
- Price, where to buy
Composition
The active substance of the preparation - salbutamol sulphate . In addition, it has a tetrafluoroethane - 1 dose.
Product form
Pharmacies can be found Ventolin aerosol (Ventolin inhaler). Moreover, Ventolin in Nebula is sold as solution for inhalation . Also, a medicine can be found in tablets and a Syrup .
Pharmacological action
Bronchodilator means.
Pharmacodynamics and pharmacokinetics
The drug is used to prevent bronchospasm . It bronchodilator - Or rather, selective beta-2-agonists . It increases lung capacity and mucociliary clearance , Activates ciliated epithelium It improves mucus secretion, expands coronary arteries Reduces the potassium content, it acts as a hyperglycemic and lipolytic agent It has an impact on glycogenolysis and insulin secretion, increases the risk of acidosis .
The drug effect rather quickly, almost 5 minutes after application (maximum - after 30-90 minutes). Duration of effect - about 5 hours.
10-20% salbutamol after use are in the lower respiratory tract. These are absorbed in the lung tissue and blood, but is not split. The remaining amount of active substance is retained in an inhaler or in the oropharynx and then swallowed and actively split when passing through the liver, with the conversion into phenolic sulphate .
The degree of association with plasma proteins - about 10%.
Received salbutamol cleaved in blood for 72 hours in the liver and excreted primarily in the urine as phenolic sulphate or unchanged. A small part is excreted in the feces.
Indications
The inhaler and a solution for him to apply to the Ventolin bronchitis chronic form, asthma and COPD with reversible airways obstruction.
Contraindications
The drug should not be used in patients with chronic Heart Failure , Hypersensitivity to the components, pregnancy , Children younger than 18 months, breast-feeding .
Side effects
Generally, among the side effects noted tremor finger Headache The appearance of anxiety. In addition, the following adverse reactions:
- hypersensitivity as hives . hypotension . angioedema . bronchospasm . collapse ;
- hyperactivity;
- paradoxical bronchospasm ;
- muscle cramps;
- hypokalemia ;
- Lactic acidosis ;
- tachycardia ;
- heart palpitations;
- expansion of peripheral vascular disease;
- arrhythmia ;
- arrythmia ;
- supraventricular tachycardia ;
- irritation of the mouth and throat.
Instructions for use Ventolin (method and dosage)
Instructions for use Ventolin warns that the drug should be used correctly, regardless of the form of release, or the healing process can go wrong.
In addition, be sure to take the medication only after consulting your doctor.
Instructions on Ventolin inhalation aerosol in the form of reports that for the use of the drug must be used nebulizer with a mask and endotracheal tube .
Ventolin Nebula, which is sold in the form of a solution for the inhaler is used without dilution. The duration of inhalation - about 10 minutes. The medicine may be diluted with sterile sodium chloride solution (0, 9%). It should be used in well ventilated rooms, because a certain amount of product into the environment.
Instructions on Nebula Ventolin inhalation recommends a dose of 2, 5 mg. If necessary, it can be increased up to 5 mg. Frequency of use - 3-4 times a day. For adult patients, if necessary, in the hospital the dosage is increased to 40 mg per day.
Aerosol for inhalation suitable for approximately 200 times use. They can use the adult patients and children from 2 years after the appointment of an expert. With a view to long-term maintenance therapy is usually administered to adults up to 200 mg 4 times a day. To prevent bronchospasm childhood used 100-200 mg (1-2 inhalation).
Syrup is assigned to patients in adulthood of 2 ml 3-4 times a day. If necessary, the dosage may be increased to 4 ml.
Overdose
At the use of the drug in doses in excess of the available hypokalemia . tachycardia , Nausea, decreased blood pressure, muscle tremors , Vomiting, agitation, respiratory alkalosis . headache . hyperglycemia . anoxemia . In rare cases appear hallucinations . tachyarrhythmia , Expansion of peripheral vascular spasms, ventricular flutter .
For treatment applied cardioselective beta-blockers But with caution, if at history have seizures bronchospasm .
Cooperation
Ventolin inhalation should not be used in conjunction with non-selective beta-adrenergic receptors . Patients with thyrotoxicosis the tool also enhances the effect of stimulants of the nervous system and tachycardia .
If you combine the aerosol and a solution for inhalation xanthines It increases the likelihood of tachyarrhythmia . FROM Levodopa and means for inhalation anesthesia increases the risk of severe ventricular arrhythmias . Together with anticholinergic medicines may increase intraocular pressure. In the appointment of diuretics and GCS increases gipokaliemicheskoe effect .
Terms of sale
The drug is sold by prescription only.
Storage conditions
Keep the medication you need in reach of children and well-protected from light. It can not be frozen or heated, the optimum temperature - not above 30 ° C.
Shelf life
The drug should be stored no longer than 2 years.
Analogs
Berotek
Foradil
Analogs of Ventolin and Nebula and Ventolin Ventolin Easy Breathing in pharmacies can get, as a rule, the following:
- Ventilor ;
- Nebutamol ;
- Salamol Ster-Neb ;
- Eco-salamol ;
- Salamol Eco Easy Breath ;
- Salbutamol ;
- Salbutamol-Intel ;
- Salbutamol Neo- .
All of them have different costs. In many cases, counterparts are less than the Ventolin.
Babies
Inhalation can be used for children relief attacks bronchospasm at a dosage of 100-200 mg (1-2 inhalation). Supportive therapy Ventolin - up to 200 micrograms 4 times a day (2 inhalations). For the prevention of use of the 100-200 mg 10-50 minutes before provoking factor (1-2 inhalation).
For children using spacers "Bebihaler" or "Volyumatik."
The clinical effectiveness of this tool in children under 18 months using nebulizer I have not been investigated.
Reviews of Ventolin
Reviews of Nebula in the Ventolin, as well as aerosol found mostly positive. Patients say his performance. Few complain of side effects and addictive. However, for those interested, hormonal or not this drug, physicians are uniquely responsible that hormones and do not recommend to use it without any special purpose.
Price Ventolin where to buy
Price Ventolin inhalation at dosages of 100 mg - about 170 rubles. As a solution, the tool is more expensive. Price Ventolin Nebula - an average of 270 rubles. Ventolin Easy Breathing costs about 150 rubles.