Description overdue on 12/19/2014

• Composition
• Product form
• Pharmacological action
• Pharmacokinetics and pharmacodynamics
• Indications
• Contraindications
• Side effects
• Instructions for use (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

The solution contained tetanus antibody with a specific action, as additional components - glycine Sodium chloride, water for injection. The level of concentration of the protein is 10-16%. The concentration level of antibodies to tetanus toxoid - not less than 50 ME / ml. Antibiotics   and preservatives are not contained in the solution.

Product form

Human tetanus immunoglobulin   is available as a solution for intramuscular administration, it is packaged into vials.

Pharmacological action

Medicine tetanus immunoglobulin - a solution of protein fraction, immunologically active, which is released from the plasma of donors using ethanol fractionation method at temperature below 0 ° C. Donors were immunized with tetanus toxoid, have been tested for the absence of antibodies to HIV   and hepatitis C virus antigen and hepatitis B drug has a property to neutralize tetanus toxin and ensures immune protection against tetanus.

Pharmacokinetics and pharmacodynamics

The largest concentration of antibodies in the blood was 24 hours after administration of the solution. The half-life of antibodies is three to four weeks.

Indications

Human tetanus immunoglobulin is assigned to provide emergency prevention Tetanus   in children and adults who for some reason have not received the full course of tetanus toxoid, as well as an unknown vaccination history.

Contraindications

You can not enter the drug at hypersensitivity   certain drugs, particularly to blood products. Do not use the medication in allergic diseases, addiction to exercise allergic reactions .

Side effects

Occasionally local reactions may be a manifestation of pain and redness at the injection solution. During the first days after administration of the agent in a patient's body temperature can be understood, may experience symptoms of allergy, in very rare cases, there anaphylactic shock .

Instructions for use (method and dosage)

Tetanus immunoglobulin injected intramuscularly into the outer part of the thigh or buttocks, and the dose should be not less than 250 ME (1 ampoule drugs), regardless of the age of the patient. If struck by a large area of ​​the wound it was contaminated or very possibly an increase in single dose twice.

Before the injection vial to survive for two hours in compliance with the temperature from 18 to 22 degrees Celsius.

To avoid foam formation, it is necessary to use a needle with a wide clearance for the set of solution into the syringe. In the opened ampoule solution can not be stored.

You do not need a skin test prior to injection.

Overdose

About overdose information shared.

Cooperation

Human tetanus immunoglobulin is not combined with other pharmaceutical drugs.

Under the influence of the reduced activity of the impact of live vaccines.

Terms of sale

Tetanus immunoglobulin sold by prescription.

Storage conditions

You can not freeze the solution. Store and transport the drug should be subject to the temperature of 2-8 ° C.

Shelf life

Shelf life - 2 years.

Cautions

You can not enter agent intravenously.

In the field of drug administration should be a means for anti-shock therapy. Within half an hour after administration of the solution should remain a person under the supervision of a specialist.

People who suffer from allergic diseases   or have a history of severe allergic reactions, it is necessary on the day of drug administration and 3-8 days after the injection to take antihistamines . Patients who suffer immunopathologic illnesses can be introduced only when receiving appropriate treatment at the same time.

All necessary information on the introduction of means of doctor brings in the appropriate form for your records.

If there was a violation of the integrity of the container with the drug have changed the physical properties of the drug, left working life, you can not administer such medication.

Babies

Where indicated administered to children.

During pregnancy and lactation

With pregnancy And while Lactation   It can be applied on the testimony and under strict medical supervision.

Reviews

Available small number of reviews on tetanus immunoglobulin. The efficiency of the preventive action of this medication.

Price, where to buy

Price package tetanus immunoglobulin (10 vials) - from 11000 rubles.