Description overdue on 05/30/2014
- Latin name: Orvirem
- ATC code: J05AC02
- Active substance: Rimantadine (Rimantadine)
- Manufacturer: JSC Corporation varnish, Russia
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions on Orvirem (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Reviews
- Price, where to buy
Composition
The syrup contains 5 mg rimantadine hydrochloride - 0 01 g, excipients ( sugar, water, sodium alginate, E122 ).
Product form
Available in the form of syrup in vials of 100 ml, in a cardboard bundle. The syrup has a thick consistency and a pinkish-red color.
Pharmacological action
Antiviral.
Pharmacodynamics and pharmacokinetics
Active substance rimantadine hydrochloride located in sodium alginate matrix cells That causes gradual release of active components means. This toxic effect of rimantadine, and the possibility of manifestation of allergic reactions is minimized.
In turn, the active agent blocks the process of virus fusion with the shell endosomal membranes , The transfer of a gene. information on the virus to cytoplasm It occurs (the process transcription of the genome ).
The substance stimulates antibodies To fight virus Catalyses processes Interferon Induction . Thanks rimantadine a reduction amount Cytokine and as a consequence, deintoxication organism decreases antigenic load and inflammation.
Indications
Prescribe medication for children from one year of age
- treatment viral diseases (mainly Influenza A );
- prophylaxis of such diseases, including during epidemics , In institutions or at home.
Contraindications
Antiviral syrup for children is contraindicated in:
- children up to one year;
- at drug allergy into components;
- at thyrotoxicosis ;
- pregnancy and lactation;
- at diabetes ;
- diseases liver, kidney .
Side effects
Are rare.
But nevertheless it possible:
- pain epigastric area diarrhea and flatulence . nausea ;
- violation of sleep, headache . neuralgia ;
- skin rash, asthenia . itchy skin .
Instructions on Orvirem (method and dosage)
The drug is administered orally after meals. The maximum daily dose of syrup is 5 mg per kg body weight.
One teaspoon typically displaces a 5 mg of drug.
Instructions for children in the prevention of:
- Children from three years to appoint 0, 01 liters per day (2 tablespoons);
- Children from three to seven years - 0, 015 liters;
- Children from seven to 14 - 0, 02 l.
Instructions for use Orvirema for the treatment of viral diseases
At the age of one year to three:
- Day 1 - 0, 01 liters, divided into 3 admission;
- at 2, Day 3 - 0, 01 l - 2 admission;
- Day 4 - 0, 01 l.
From three to seven years:
- Day 1 - 0, 015 liters - 3 admission;
- at 2 and 3 - 0, 015 l - 2 admission;
- Day 4 - 0, 015 l.
Children from 7 to 14 years:
- first day - 0, 02 l - 3 admission;
- second and third - 0 02 n - 2;
- fourth - 0, 02 l.
Overdose
No cases have been reported.
Cooperation
In a joint application with drugs by epilepsy Consult a specialist wasps.
The drug enhances the effect of caffeine on central nervous system .
Efficacy is reduced when combined with paracetamol and aspirin .
Terms of sale
In order to buy the drug need a prescription.
Storage conditions
In the reach of children, dark, cool place.
Shelf life
3 years.
Cautions
At diabetes it should be noted that the drug contains a large amount of sugar.
Analogs
Remavir
Rimantadine
Rimantadine, arbimaks, rimantadine, protfenolozid, Jodantipyrin, aperflyu, novirin, cytokine arbidol, Alguire, Avonex, amizon, anaferol, Tamiflu Inferon .
Reviews Orvireme
Reviews on Orvirem for children. Many parents prefer to use syrup for children for treatment Flu , The drug speeds up the healing process, prevents unwanted complications. It is often prescribed by doctors. However, the side effects often manifest themselves in the form of allergies . Some believe the medication for the prevention of influenza inappropriate, preferring folk and other ways to strengthen the immune system.
Price Orvirema (Where to buy)
Syrup for children is relatively inexpensive.
The average price Orvirema for children is about 170 rubles per 100 ml.