Description overdue on 07/21/2014
- Latin name: Proteflazidum
- ATC code:
- Active substance: The extract is a mixture of herbs
- Manufacturer: SPC "Ecopharm", Ukraine
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use Proteflazid (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
The structure of 100 ml of the drug enters the liquid extract mixture of plants: Soddy grass pike and reed grass ground .
It contains not less than 0 32 mg flavonoids rutin And not less than 0, the amount of 3 mg carboxylic acids in terms of malic acid.
In addition, in this product include as an additional ingredient ethanol 96%.
Product form
Proteflazid available as a solution for oral administration and topical. This dark green liquid which has a specific odor. Long periods of storage can be formed gel structure that during shaking collapses.
The droplets contained in a plastic or glass bottle, 25, 30 or 50 ml.
Pharmacological action
Flavonoids wild grasses which are composed of means capable of inhibiting the DNA polymerase and thymidine kinase (these enzymes are specific viruses). These processes occur in the cells of the body who have been infected by viruses. As a result of inhibition of these enzymes stops the replication of viral DNA. As a result, he ceases to multiply in the cells.
Under the influence of Proteflazid being strengthened nonspecific immunity . Interferon . This increases the overall resistance of the body as viruses and bacteria.
The product has properties antioxidant In view of what stops the accumulation in the body of lipid peroxidation products. In long-term daily treatment means normalizes the immune status. Therefore Proteflazid can be used for an extended period for the treatment of chronic recurrent infections.
Pharmacodynamics and pharmacokinetics
Upon receiving means of its partial absorption occurs in the stomach, and then the remaining part is absorbed in the small intestine.
A small part breaks due to flavonoids presystemic metabolism That is, during the first pass through the liver. Their principal amount gets into the cells of organs and tissues, getting in those cells that have been infected with the virus.
In those cells which were not infected and, therefore, they do not have high rates of virus activity of enzymes, means no effect.
The half-life of an adult human is from 5 to 9 hours, so it is reasonable to remedy three times a day.
Indications
The tool is used in the following diseases and conditions:
- viral infections That it was provoked simplex virus Herpes first and second types ( vesicular dermatitis . eczema . faringotonzillit . . meningitis and encephalitis . h, genital herpes );
- herpes zoster ;
- infectious diseases that occur as a result of exposure to the virus herpes fourth type , Both acute and chronic;
- infectious diseases, provoked by a virus herpes fifth type ;
- hepatitis B and FROM (complex therapy);
- viral, fungal, bacterial infections (complex therapy);
- flu . SARS (prevention, treatment);
- HIV infection and AIDS (complex therapy).
Contraindications
Proteflazid not apply if the notes:
- intolerance to certain ingredients PM;
- exacerbation gastric ulcer or duodenal ulcer .
Side effects
In most cases, side effects of the treatment agent is not observed. gastrointestinal disorders Who accompanied vomiting . nausea , Pain in the epigastric region. At 3-10 days of therapy showed an increase in body temperature to 38 ° C.
In rare cases, there is development allergic reactions Mostly they are manifested in the form of erythematous rash on the skin. Rarely show headache Which disappeared after the PM dose has been adjusted.
During the treatment of hepatitis B in approximately 15% of people with cytolytic syndrome increased activity aminotransferases .
People with chronic form gastroduodenita , Manifested exacerbation of the disease, development .
If Proteflazid applied topically, can develop itching sensation . burning . dryness skin. In this case it is necessary to reduce the concentration of the drug.
Instructions for use Proteflazid (method and dosage)
Instructions on Proteflazid provides that the drops are applied to the oral intake of sugar or a piece of bread. How to take the drug, lurid detail doctor prescribed a course of treatment.
Standard treatment with Proteflazid instructions for use paints as follows: in the first week of treatment must be taken every day to 15 drops of this dose is divided into three stages. The second and third week of treatment - 30 drops, which is to be divided into 3 doses.
In general, the treatment lasts for one month, if needed, can be a repeated course of therapy.
For children, the dosage Proteflazid determined by the physician. Typically, 1 drop per day receives a child from birth to age two. Children between the ages 2-4 years was prepared in the first week of therapy 1 drop twice a day, in the second - 2 drops twice a day. Children 4-6 years obtained in the first week of therapy with 2 drops three times a day, in the second - 3 drops three times a day. Children aged 9-12 years obtained in the first week of therapy 4 drops three times a day, in the second - 7 drops three times a day. After 12 years of age a child receives in the first week of treatment 5 drops three times a day, the second - 8 drops three times a day.
Due to the presence in the composition of ethyl alcohol to children under the age of six drops give, after dissolving the desired dose of a small amount of sugar water.
If patients have frequent recurrences of infectious diseases, the course of treatment is practiced 3-4 Proteflazid year. If the infection is latent, it shows two such courses of treatment per year.
To this end, 3 ml of the drug is dissolved in 20 ml 0.9% NaCl. The solution obtained is necessary to moisten the gauze tampon which is then inserted into the vagina. This procedure is repeated twice a day for at least two weeks.
Overdose
There are no data on overdose Proteflazid.
Cooperation
There is information about the possibility and expediency of simultaneous application Proteflazid with antibiotics, as well as drugs that provide anti-fungal effects during the treatment of viral and fungal and viral and bacterial infectious diseases.
No information about adverse interactions with other medications.
Terms of sale
The tool can be purchased by prescription.
Storage conditions
Proteflazid should be stored in a dark place, the air temperature must not exceed 25 ° C.
Shelf life
Shelf life - 3 years
Cautions
If the drug treatment has been an increase in body temperature to 38 ° C, it is necessary for a certain period (2-3 days), reduce the dose twice.
Receiving funds does not affect the speed of reaction, so the negative impact on the ability to manage traffic and work with the precise mechanism is not marked
Analogs Proteflazid
Analogues of this tool on the effects of drugs on the body are: Herpes simplex . Arbidol . Detoksopirol . Ingavirin . Imustat . Armenikum . Ferrovir . Kagocel . Panavir . Flavozid . Jodantipyrin . Any analog of the drug can be used instead Proteflazid only after consultation with the doctor.
Babies
Apply a treatment for children may be from the first days of life.
With alcohol
There is no strict contraindications relating to the co-administration Proteflazid and alcohol.
Proteflazid during pregnancy and lactation
In any of the trimesters of pregnancy, this drug is prescribed to women with care, the physician must be sure to assess the benefits and potential risks to the fetus and mother. Negative effects on the fetus in the course of pre-clinical studies were found. The experience of treatment with the second and third trimester of pregnancy and during breast breast milk indicates the absence of adverse effects.
Reviews Proteflazid
There are numerous positive reviews of physicians and patients about the efficacy of this agent in the treatment of infectious diseases. In particular, parents noted that the drops which have been used for children who had a pronounced antiviral effect.
immunomodulator : In a review of Proteflazid often it is that after the course of this treatment the patient became sick much less often.
A marked positive effect in the treatment of Proteflazid herpetic infections , Reducing the frequency of relapses after this treatment. As negative impressions about the medicine indicated its unpleasant taste and high price.
Price Proteflazid where to buy
Price Proteflazid in Kharkov, Odessa, Donetsk and other cities ranges from 200 to 230 hryvnia per 30 ml vial.
Buy Proteflazid in Moscow can be an average of 2,000 rubles.