Description overdue on 09/22/2014

  • Latin name: Instenon
  • ATC code: C01EX
  • Active substance: Hexobendine dihydrochloride (Hexobendinum dihydrochloride), Etofillin (Etofylline), etamivan (Etamivan)
  • Manufacturer: ALKALOID (Macedonia); HAFSLUND NYCOMED (Austria)
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  • Composition
  • Product form
  • Pharmacological action
  • Pharmacodynamics and pharmacokinetics
  • Indications
  • Contraindications
  • Side effects
  • Instructions for use instenon (method and dosage)
  • Overdose
  • Cooperation
  • Terms of sale
  • Storage conditions
  • Shelf life
  • Analogs
  • During pregnancy (and lactation)
  • Reviews
  • Price, where to buy

 Instenon

Composition

The preparation contains as active substances hexobendine dihydrochloride . etofillin . etamivan .

This medicine tablets has the following auxiliary components: talc . magnesium stearate . corn starch . lactose monohydrate . pregelatinized starch . A solution intended for internal administration is such further agents as disodium edetate . Water for Injection . propylene glycol .

Product form

This preparation is produced in the form of tablets, which are coated, as well as a solution for injection and dragees.

Pharmacological action

Medicine for the normalization of cerebral blood flow and cerebral metabolism .

Pharmacodynamics and pharmacokinetics

Effect of the drug is determined by the sum of the characteristics of its active ingredients. Hexobendine   improves metabolism   in the brain and heart, that normalizes blood supply. Etofillin   has a positive inotropic diuretic and bronchospasmolytic impact It stimulates the nervous system. Etamivan   contributes to the improvement of the system activation reticular formation   brain stem, which causes the activation cortical   and autonomic functions .

Indications

Indications for use drugs are as follows:

  • a change in the intelligence atherosclerosis ;
  • stroke ;
  • stenosis   and obliteration of the cerebral arteries ;
  • resistant cerebral hypertension ;
  • cerebrovascular insufficiency ;
  • a state of confusion and disorientation;
  • postapopleksicheskoe state ;
  • memory decline   in old age.

Contraindications

The drug is contraindicated in case of hypersensitivity to its components, epilepsy , Bleeding in the brain, a state of extreme excitement, seizures And symptoms of increased intracranial pressure.


With care prescribe the medicine after a stroke and stenosis   carotid artery because arteriosclerosis .

Side effects

When using the drug may experience the following side effects: flushing of the face , Lowering blood pressure, headache .

Instructions for use instenon (method and dosage)

In chronic cerebral insufficiency   for those who are appointed Instenon, application guidelines recommend the use of inside after or during meals 1 tablet or tablet 2-3 times during the day for 3-4 weeks.

In acute Cerebral ischemia   and hypoxia   prescribe intravenous drip 2 ml. For this Instenon dissolved in 200-250 ml of glucose (5%) or in saline. Take the medication 1-2 times during the day. Treatment designed for 3-5 days until the desired effect.

In other situations, usually administered intramuscularly or intravenously administering 2 ml (Instenon diluted in 200-250 ml of glucose (5%)). The drug is taken 1-2 times during the day. Treatment is intended for 7-10 days.

In order to avoid a decrease Blood Pressure   the solution is used for internal administration slowly.

Instructions for use instenon reported that the pills taken by mouth without chewing. Allowed to drink a certain amount of liquid. The course can be calculated, and for 6 weeks. The dosage and duration of treatment are determined by an expert.

Overdose

In applying the drug in high doses can be headache   and hyperemia .

Cooperation

Conjunction with drugs which reduce the activity Platelet . antiplatelet   instenon effect can be enhanced.

Caffeine in high doses can reduce the effectiveness of the drug. So the treatment instenon better to avoid drinking large amounts of beverages such as tea and coffee.

Terms of sale

The drug is available on medical prescription.

Storage conditions

Store this medication must be well protected against the penetration of sunlight and out of reach of small children. Optimum temperature - 15-25 ° C.

Shelf life

Keep the medication should be no longer than five years.

Analogs

Match code ATC 4th level:
  •  Instenon
 Pumpan
  •  Instenon
 Barboval
  •  Instenon
 Korvalment
  •  Instenon
 Validol

As instenon analogs may be administered in different cases, the following drugs:

  • Antifront ;
  • Armadin ;
  • Boluses Huato ;
  • Glycine ;
  • Keltikan ;
  • Cortexin ;
  • Mexidol ;
  • Meksiprim ;
  • Neurotrophins ;
  • Nucleo CMF Forte ;
  • Tryptophan ;
  • Citoflavin .

Each of these tools has its indications, contraindications and features. If you need to replace Instenon analogues are prescribed.

Some experts also recommend that patients Instenon Forte. In fact, this is the same drug, but with a high content of active substances.

Instenon during pregnancy (and lactation)

Instenon at pregnancy   and breast-feeding   It can be used only on strict conditions.

Reviews instenon

Instenon reviews of doctors receives, mainly positive . This drug rarely gives any complications, so that it is administered even to children. The only caveat, which usually mark reviews instenon this addictive drug in the body. Thus, it is only a preparation course, which is not designed for prolonged use.

Price instenon where to buy

Price instenon tablets (30 pieces per pack) - 200 rubles. The solution for injection (30 vials) and costs about 200 rubles. Instenon Forte sold at a high cost - about 335 rubles.

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