Description overdue on 01/08/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use tablets Zoreks Morning (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Babies
• With alcohol
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

Each tablet contains 0 324 g acetylsalicylic acid 1 474 g citric acid , 2, 013 g of   sodium bicarbonate And adjuvants: 0, 08 g of succinic acid, 0 048 g of sodium benzoate, 0, 001 g povidone, 0, 04 g of lemon flavor and 0 02 g of flavor " lime ".

Product form

Available in the form of effervescent tablets, 2 pieces in Valium outline packages (Streep), made of the composite material, the tablets in a strip separated by a perforation. Squeak put on 5 pieces in cardboard boxes.

Pharmacological action

Morning has Zoreks analgesic . antipyretic   and inflammatory action .

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The drug belongs to Zoreks Morning NSAIDs   combined composition. Acetylsalicylic acid   It has an inhibitory effect on cyclooxygenase   1 and 2, and as a result gives synthesis prostaglandins It is anti-inflammatory . pyretic . analgesic   action slows platelet aggregation .

Sodium bicarbonate   It plays an important role in neutralizing free   hydrochloric acid   in the stomach. This is necessary to reduce the risk of negative consequences resulting from the use of acetylsalicylic acid.

The role of the citric acid is to accelerate the absorption from the digestive tract of a medicament.

Pharmacokinetics

At this time there are no data on the pharmacokinetics Zoreks morning.

Indications

By the indications for use Zoreks Morning medications include:

• headache arising in the case of alcohol withdrawal syndrome ;
• mild or moderate expression of pain in adults who have different origins (eg, pain with migraine . toothache . neuralgia . muscle aches );
• elevated body temperature during the development of common cold or other infectious and inflammatory diseases (for persons under 15 years).

Contraindications

Zoreks forbidden to take in the morning:

• erosive and ulcerative lesions of the gastrointestinal tract   (during an exacerbation) gastrointestinal bleeding ;
• "Aspirin" asthma;
• concomitant use of medication Methotrexate   at a dose of 15 mg per week;
• severe hepatic impairment;
• severe renal impairment;
• hemorrhagic diathesis   (in this group of diseases are all kinds Hemophilia . telangiectasia . von Willebrand disease . gipoprotrombinemii . thrombocytopenic purpura . thrombocytopenia );
• dissecting aortic aneurysm ;
• deficit glucose-6-phosphate dehydrogenase ;
• portal hypertension ;
• pregnancy (during the I and III trimester);
• breastfeeding;
• hypersensitivity to acetylsalicylic acid   and other NSAIDs .

The drug should not be prescribed as an antipyretic to those who have not reached 15 years, especially in cases of acute respiratory infections, which are caused by viruses, as in such cases there is a considerable risk of Reye's syndrome Which is shown encephalopathy and spicy steatosis As well as rapid development acute liver failure .

It is necessary to exercise caution when using the drug in patients with hyperuricemia . urate nephrolithiasis . gout . gastric ulcer and duodenal ulcer   (as in case of exacerbations, and with a history of references to these diseases). Also, the drug is prescribed with caution in cases where there is a patient Heart Failure   decompensated.

Side effects

The drug affects the body as a whole, so many systems of the body can manifest undesirable symptoms caused by side effects of the drug:

• Digestive system : Can significantly reduce your appetite, have pain in the abdomen, pain in the stomach, feeling nausea . vomiting . diarrhea , Signs of bleeding in the gastrointestinal tract. Signs of bleeding may be obvious (for example, black stool, vomiting blood), and can be hidden. But in any case there is a danger of iron deficiency anemia . Also, you may experience erosive and ulcerative lesions of the gastrointestinal tract Even with perforations . In rare cases, it may impair the functioning of the liver, which is manifested by increased levels Hepatic transamina s   and bilirubin .
• Central nervous system   and senses : You may experience dizziness, tinnitus. In cases where the drug is taken for a long period of time likely to cause headaches, disorders of the visual and auditory aids.
• Hematopoietic system and hemostasis : A side effect of the drug may be the development of aplastic anemia . agranulocytosis . pancytopenia . hemorrhagic syndrome . thrombocytopenia . If you take medication for a long time can reduce the level of platelet aggregation   and the rate of blood clotting (development   hypocoagulation ).
• The urinary system : The consequence of the use of high doses of the drug may develop giperoksalaturii   and the formation of   Calcium oxalate   urinary stones may be damaged glomerular   kidney, develop renal failure ; and with prolonged use of the drug - papillary necrosis .
• It is also possible to develop allergic reactions : Skin rash, angioedema . bronchospasm . Stevens-Johnson syndrome , Toxic epidermal necrolysis   (or Lyell's syndrome ).

Instructions for use tablets Zoreks Morning (method and dosage)

The tablets are taken orally Zoreks morning. For this tablet dissolved in a glass of water and drink. Single dose for adults and children under 15 years - 1-2 tablets with a break between doses of 4 to 8 hours. The maximum tolerated dose per day - 8 tablets.

According to the instructions on Zoreks morning, the length of the treatment period should not be longer than 7 days in the case, when the drug was appointed as an anesthetic, and not to exceed 3 days, if used as an antipyretic.

Overdose

The first symptoms of overdose are signs of arousal of the central nervous system, the emergence of dizziness, severe headache . gastralgii , Ringing in the ears, decreased hearing acuity, functional disorders of the visual system, the occurrence of nausea . vomiting . shortness of breath . In further stages of the following is characterized by a feeling of drowsiness, convulsive status . anuria , Inhibited until the onset of consciousness Coma , Development respiratory failure , Violations of water-electrolyte metabolism.

If signs of poisoning need to induce vomiting or stomach wash, then drink the required amount of pills Activated Carbon   or another drug with a similar action, drink a laxative and seek medical advice. Further treatment is carried out in a specialist unit.

Cooperation

The drug has the property to enhance the toxicity Methotrexate , Cause an increase in effect opioid analgesics Other NSAIDs . Heparin , Certain anticoagulants . sulfonamides . thrombolytics . platelet aggregation inhibitors . triiodothyronine . reserpine . It also reduces the effect of uricosuric agents (these include benzbromarone   and sulfinpirazon ) Means that reduce arterial pressure And diuretics (e.g. spironolactone . furosemide ).

Addicting glucocorticosteroids . ethanol   or ethanol-containing medicines together with pills Zoreks Morning causes an increase in the damaging effect on the mucous membrane of the gastrointestinal tract, increases the risk of gastrointestinal bleeding.

It increases the concentration of drug in blood plasma barbiturates . Digoxin And lithium preparations.

Addicting antacids Which contain magnesium or aluminum hydroxide, resulting in slower absorption, and deterioration of acetylsalicylic acid.

Paracetamol   It increases the likelihood of adverse side effects.

Terms of sale

Allowed to sell without a prescription.

Storage conditions

In dry and protected from light place. The air temperature must not exceed 25 ° C.

Shelf life

3 years.

Cautions

Caution should be exercised when using the drug to people with a predisposition to gout , so how acetylsalicylic acid , Part of the drug, reduces excretion Uric acid   with the body, and this may provoke an acute attack of this disease.

If the drug is used for a long time, it takes time to monitor the state of peripheral blood, liver function and to check for hidden blood in the stool samples.

It is worth remembering that one dose of the drug Zoreks Morning contains 933 mg of sodium, so should be used with caution for people who are on a salt-free diet.

Babies

You can not give to children under the age of 15 years.

With alcohol

Drinking alcohol during treatment can cause gastrointestinal bleeding.

During pregnancy and lactation

Prohibited use of the drug during the I and III trimesters of pregnancy. During the II trimester of pregnancy is possible one-time use of the drug, but only in cases where the risk to the fetus is smaller than the benefit to the pregnant woman.

If you want to use the drug during lactation, the period of treatment should stop breastfeeding.

Reviews

Reviews about the drug Zoreks Morning enough. Most often it is drunk as a hangover pill. There are reviews of its effectiveness, but there are also many who say the occurrence of side effects of the drug, especially allergic reactions.

Price, where to buy

Zoreks Morning is in pharmacies from 160 to 218 rubles.