Description overdue on 09/20/2014
- Latin name: Blemaren
- ATC code: G04BC
- Active substance: Citric acid + potassium bicarbonate + Sodium Citrate
- Manufacturer: The developer and copyright: Esparma GmbH, Germany The manufacturer: Allfamed Farben Arzneimittel GmbH, Germany
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications for use of the drug
- Contraindications
- During pregnancy (and lactation)
- Side effects
- Blemaren, instructions for use (method and dosage)
- Overdose
- Cooperation
- Cautions
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- With alcohol
- Reviews
- Price, where to buy
Composition
The preparations contain the active ingredients: citric acid dehydrated - 39, 90g, potassium bicarbonate - 32 25d sodium citrate Dehydrated - 27, 85g, and adjuvants.
Product form
This medication is available in effervescent tablets packed 20 pieces in a plastic tube. Also included test paper and check your calendar.
Pharmacological action
Blemaren has nefrolitoliticheskim, alkalizing urine action.
Pharmacodynamics and pharmacokinetics
It allows the use of this drug to dissolve and prevent the formation of uric acid stones, by means of alkalinization of the urine to the optimum pH 6 6-6 8. As is known, when the urine pH is 6, 6-6, 8 is a significant improvement in the dissolution of the salts of uric acid. Also decreases the excretion Calcium It improves solubility calcium oxalate consisting of urine, it inhibits the formation of crystals that prevents calcium oxalate stones.
The bioavailability of the drug is almost 100%. Excretion of substances from the body occurs by means of the kidneys.
Indications for use of the drug
Treatment Blemarenom prescribed when necessary:
- dissolve uric acid and calcium oxalate stones and notify their education;
- the solution was mixed Uric acid, calcium oxalate stones With oxalate to 25%;
- perform alkalinization of the urine of patients who receive cytostatics and means able to increase the excretion of uric acid;
- spend symptomatic therapy porphyria skin.
Contraindications
The main contraindications to the reception blemaren are:
- hypersensitivity;
- metabolic alkalosis ;
- acute and chronic forms renal failure ;
- urinary tract infection , Caused by a the microorganisms that break down urea ;
- compliance with strict salt-free diet, for example, in severe hypertension;
- urine pH above 7;
- age of patients less than 12 years, since the clinical experience for this age group has not been studied.
Pregnancy and lactation
Specialists are not confirmed by the data provided on the side effects of the drug during Lactation or pregnancy. Therefore, in such times, for the purpose of the preparation required consultation with a physician.
Side effects blemaren
In the treatment with this drug may experience different side effects:
- puffiness Due to sodium retention;
- dyspepsia ;
- metabolic alkalosis ;
- allergic reactions .
Blemaren, instructions for use (method and dosage)
The tablets are for oral use, after eating the food. For this, the drug was dissolved in 200 ml of any liquid - tea, fruit juice or water.
According to the instructions for use blemaren, the daily dosage can be 2-6 tablets , Receipt of which must be evenly distributed throughout the day. Choosing the right dosage saves pH throughout the day within a 6, 2-7 - if you want to dissolve uric acid stones, 7, 5-8, 5 by dissolving cystine stones, at least 7 - Therapy cytostatics 7, 2-7, 5 - conducting the treatment of porphyria. When the pH of the urine is less than this, the dosage is increased, and high performance - decrease. Average duration of treatment can be 4-6 months.
During therapy is necessary to monitor the effectiveness, that is to determine the pH of urine, at least 3 times a day, each dose before reception by using the test paper. The results in the paper should be compared with the scale and record figure in the calendar control.
Overdose
No cases of overdose Blemarenom not reported.
Cooperation
Blemaren and combination products containing citrate and aluminum, sometimes causes increased absorption of aluminum. It is necessary to sustain the interval between receptions of about 2 hours.
Possibility of weakening the effectiveness cardiac glycosides As Blemarene contained in the substance, such as potassium.
Concomitant use of drugs that lower blood pressure, for example, aldosterone antagonists, potassium-sparing diuretics, ACE blockers or NSAIDs and analgesics , Can reduce the excretion of potassium.
Cautions
The average daily dosage - is 4 tablets contained almost 0, 9, and 1 g of sodium and 5 mg of potassium, so it is necessary to consider the treatment of patients for whom salt intake is restricted.
Admission blemaren allowed in chronic renal failure if it does not set a delay of potassium ions.
During the dissolution of uric acid stones is necessary to strictly observe the daily dose, because the increase in pH over 7, resulting in the deposition of uric acid crystals in the phosphate preventing its subsequent dissolution.
It is also recommended to limit the consumption of foods rich in protein and purine bases, providing a complete fluid intake - about 1 5-2l.
Treatment does not have much influence on the ability to drive vehicles or machinery that require special attention.
Terms of sale
Tablets without a prescription.
Storage conditions
For storage of the drug requires a cool, dry place, protected from the children.
Shelf life
4 years.
Analogs
Madder dyeing
Uronefron
Rovatineks
Main counterparts blemaren - it K-Na gidrogentsitrat and Soluran .
There are also drugs with a similar action, for example: Urolesan, Cystenalum, Phytolysinum, Uronefron and others.
Alcohol
In the treatment of this drug, alcohol is not a direct contraindication, but this should not be abused. The fact that a large amount of alcohol can slow down the metabolism and thus excretion and effectiveness of the drug.
Reviews Blemarene
This drug is widely applied in clinical practice. In this patient testimonials about Blemarene report that its effectiveness is evident in cases where they strictly adhere to therapeutic regimen assigned to a specialist.
Many patients say that they prescribed the drug for the treatment of kidney stones due to pH shift toward acidity. Completely eliminate this disease has helped it course therapy with this medicine.
Also found in the reviews of Blemarene gout, when patients attempt to get rid of the problem. Subsequently, however, they were forced to see a doctor, and after treatment with this drug experienced significant relief.
Reviews of the Blemarene devoted more than a forum where you can find a detailed description of therapeutic schemes using this drug and mineral water. This treatment helps to restore the pH level of urine and normalize health.
Price blemaren where to buy
The drug can be bought in Moscow in pharmacies without a prescription at a cost of 635-990 rubles per 80 pieces.
Price blemaren in Ukraine varies between 288-350 USD.