Description overdue on 20/06/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

The composition of 0, 5 mL dose contains the following components: adsorbed tetanus toxoid Adsorbed diphtheria toxoid Adsorbed pertussis toxoid Adsorbed recombinant HBsAg protein Adsorbed pertactin Adsorbed filamentous hemagglutinin , Poliovirus type 1 (Mahoney), poliovirus type 2 (MEF-1), poliovirus type 3 (Saukett).

The vaccine composition also has additional components: Medium 199 (M199) with amino acids, sodium chloride, water for injection, aluminum phosphate, aluminum hydroxide, polymyxin B sulfate, polysorbate 20 and 80, sodium phosphate, neomycin sulfate, glycine, formaldehyde, potassium chloride potassium dihydrogen phosphate.

Product form

Available in the form of suspension Which is used for injection. It is placed in a disposable syringe. Also available in the form of Lyophilized Powder   white color, which must be mixed before use. After dilution formed cloudy liquid. The slow sedimentation process gives a white precipitate. The powder was placed in a vial.

Pharmacological action

Infanrix Hexa vaccine used to protect against Tetanus . Diphtheria . pertussis . The vaccine meets the requirements of the WHO, which relate to the production of vaccines to protect against diphtheria, tetanus, whooping cough; vaccines Hepatitis B Which are produced by recombinant DNA and inactivated polio vaccines; conjugate vaccines used for the prevention of infectious diseases that provokes Haemophilus influenzae type b .

During the clinical trials of the drug were obtained the following results: after one month, after three doses were administered Infanrix hexa (primary vaccination) antibody titers to diphtheria and tetanus were equal ≥0, 1 IU / ml in 98, 5 100% of children. The immune response to each of the three pertussis antigens of 97, 2-99, 3% (first), 95, 2-100% (second) and 95, 9-99, 3% (third).

Pharmacodynamics and pharmacokinetics

No information is provided on the pharmacokinetics and pharmacodynamics of the drug.

Indications

Infanrix Hexa is used to vaccination for the prevention of some diseases - Tetanus . Diphtheria . pertussis . Polio . Hepatitis B And diseases that develop under the influence of the pathogen Haemophilus influenzae type B .

Contraindications

Vaccination with Infanrix hexa is not carried out for people who have indicated a high level of sensitivity to the active substance or to any other components of the drug.

You can not enter the PM, who already showed signs of high sensitivity after vaccination against whooping cough, tetanus, diphtheria, hepatitis B, polio or diseases that were caused by the Haemophilus influenzae type B (Hib).

Do not use this drug for the vaccination of children who have diagnosed encephalopathy   of unknown cause within seven days after the inoculation with the vaccine koklyushsoderzhaschey. In this case it is necessary to carry out subsequent vaccination agents which do not have a composition koklyushsoderzhaschego component.

No vaccine is carried out in the presence of a child's acute diseases, both infectious and non-infectious. This situation is a temporary contraindication for vaccinating the baby. Routine vaccination is carried out not earlier than 14 days field a full recovery of the child. If there is mild course of the disease, vaccination can be done as soon as indicators of body temperature normal.

Side effects

After vaccination side effects include the following:

• Local reactions such as swelling pain, hyperemia ;
• Systemic reactions in the form of fever . anorexia . irritability . sleepiness .

In rare cases, the allergic symptoms were noted, including anaphylactoid reactions.

It is extremely rare for vaccination with pertussis preparations have been cases collapse . seizures . shock-like state . Convalescence after such reactions took place without complications.

Instructions for use (method and dosage)

Instructions for Infanrix hexa during primary vaccination following: only the vaccine is administered three times a dose of 0, 5 ml. Child drug is administered in a pattern 2-3-4 months or 3-4-5 months, or in 2-4-6 months. Can be administered two doses (3 months and 5 months). Instructions for use means provides that between doses must pass at least one month.

If a child gets after birth vaccinated with a vaccine against hepatitis B, Infanrix Hexa is used as a substitute for additional doses of hepatitis B vaccine for children after six weeks of age.

Revaccination is carried out once a child of 18 months. If necessary, on the advice of a specialist vaccination may be carried out at another time, but after the initial vaccination must be at least six months.

It is recommended to be administered Infanrix hexa in the middle third of the thigh. Enter drug intramuscularly, deeply, with the introduction of each dose is the place you need to alternate. We can not categorically be administered this drug subcutaneously or intravenously. Never mix Infanrix hexa in the same syringe with any other vaccine.

Before the introduction of the means needed to thoroughly evaluate its appearance. In the presence of foreign substances, or any other means to introduce the changes should not be.

It is desirable to introduce the drug after it reaches room temperature.

Before the introduction of the syringe should be shaken to form a uniform, homogeneous whitish suspension.

Infanrix hexa is not used to vaccinate children after the age of three.

Overdose

Data on overdose of vaccine no.

Cooperation

If the patient has previously held immunosuppressive treatment, or he says the state Immunodeficiency May ultimately not be achieved the expected immune response after vaccination.

There is insufficient data on the interaction Infanrix Hexa vaccine that protects against Measles . Rubella . mumps .

With simultaneous use of Infanrix hexa and vaccines Prevenar   no change was noted in the production of antibodies against each of the antigens that are part of these vaccines when prescribed for primary vaccination trehdozovoy scheme.

But it is more common in children who received at one time and Prevenar Infanrix hexa, fever was observed causing a significant increase in body temperature.

Terms of sale

Sold in pharmacies by prescription.

Storage conditions

The drug should be kept in a dark place, and the storage temperature should be 2-8 ° C. During transportation of the vaccine need to comply with the terms of its storage. Frosting drug should not be.

Shelf life

Store the tool can be 3 years.

Cautions

Prior to vaccination it is imperative to conduct medical history, especially with regard to previous vaccination and symptoms of adverse reactions. Also, before the introduction of funds held inspection of the child.

It is necessary to enable the implementation of necessary actions in view of the existence of opportunities for development anaphylactic reactions .

With care prescribe a drug for those who have diagnosed thrombocytopenia   or marked blood coagulation disorders Since there is a possibility of bleeding after the injection.

Infanrix hexa in the present neomycin   and polymyxin In view of this need to be very careful to use the vaccine for those who have marked sensitivity to these antibiotics.

The vaccine may not prevent infections, which are caused by viruses hepatitis A, C, E As well as other pathogens triggers the development of liver disease. Also, it does not develop immunity to diseases that develop due to exposure to other types of Haemophilus influenzae , Or meningitis Which cause other microorganisms.

Infanrix hexa can be administered to a tendency to Febrile seizures And if you have a family history of sudden death syndrome place, seizures and adverse events after administration of vaccinations.

Vaccination is allowed HIV infection .

Analogs

Infanrix hexa analogs are drugs, which is composed of the same ingredients. However, each vaccine, depending on the availability of certain components of the immune system generates certain diseases. Thus, the vaccine Infanrix IPV creates protection pertussis . Tetanus . Diphtheria . Polio . Vaccination Infanrix aims to create immunity against pertussis, tetanus, diphtheria.

Is it better or Infanrix hexa Pentaxim?

Vaccination drug Pentaxim carried out at the right scheme provides protection against whooping cough, tetanus, diphtheria, polio, and Haemophilus influenzae. What kind of prefer a vaccine for immunization the child, parents should determine, after consultation with the doctor, and all the features of the health of the baby.

Babies

The drug is used for vaccination of children under three years of age.

During pregnancy and lactation

Given that adults with the aim of vaccinating drug is not indicated, there is no data on the effect of components means the body of pregnant women and nursing mothers.

Infanrix hexa reviews

Responses to the vaccine Infanrix Hexa, which are niche sites and forums leave parents often positive. It is noted that the complications after the administration of the vaccine are rare. Basically, as the short side reactions appear fever, tearfulness, local reactions, which rapidly disappear. It mentioned as a drug Infanrix IPV   as a means that is well tolerated and does not cause serious side effects in children.

Doctors also noted the effectiveness of which provides the vaccine Infanrix hexa. Komorowski and other pediatricians emphasize that to achieve the desired effect of the vaccine should be administered only under the established scheme.

Infanrix hexa price, where to buy

Buy in Moscow vaccine may be as low as 700 rubles a package with a single dose of the drug.