Description overdue on 12/15/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Kapsluly Celebrex: instructions for use (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• Reviews
• Price, where to buy

Composition

One capsule contains 200 milligrams of the drug celecoxib . As auxiliary components present croscarmellose sodium, povidone K30, sodium lauryl sulphate, lactose monohydrate and magnesium stearate. The shell consists of titanium dioxide and gelatin.

Product form

The drug comes in the form of gelatin capsules, the contents of the capsule is white.

Pharmacological action

Celecoxib inhibits the activity TSOG2 and also a bit overwhelming TSOG1. Has anti-inflammatory, antipyretic   and painkiller action, reduces the risk of colon cancer.

The use of this drug is much safer than the use of other NSAIDs, since it hardly causes a risk of gastroduadenalnyh ulcers and does not disturb the natural processes associated with prostaglandin E1 class in the stomach and intestines.

Pharmacodynamics and pharmacokinetics

The drug is well absorbed from the digestive tract empty stomach. The maximum concentration is reached after about two or three hours. Use of fatty food slows the absorption of the drug for four hours. Provided for 99 percent of the liver, can penetrate the blood-brain barrier.

Indications

What does the pill Celebrex? Indications for use drugs are as follows:

• acute pain   in the back;
• algomenorrhea ;
• arthritis   (osteoarthritis, rheumatoid arthritis), spondylitis ;
• complex therapy of patients with familial adenomatous polyposis .

Contraindications

The drug should not be taken if:

• condition after surgery for coronary bypass;
• allergic reactions to acetylsalicylic acid or other NSAIDs;
  hypersensitive to sulfonamides or components of the drug;
• lactating ;
• pregnancy ;
• heavy renal failure ;
• heavy hepatic insufficiency ;
• severe cerebrovascular diseases;
• peripheral artery disease;
• Heart Failure ;
• gastrointestinal bleeding;
• sharpened peptic ulcer ;
• hypersensitivity   to the drug;
• the age of 18.

Side effects

Frequently observed:

• skin rash   and itch ;
• upper respiratory tract infection, sinusitis . rhinitis . pharyngitis . cough   and bronchitis ;
• urinary tract infections;
• insomnia , Increased muscle tone, dizziness ;
• dental diseases, flatulence . dyspepsia . diarrhea , Abdominal pain;
• peripheral edema ;
• flu-like symptoms, exacerbation allergies .

It is not often observed:

• hives . alopecia ;
• drowsiness , Anxiety;
• vomiting ;
• blurred vision, noise in ears ;
• tachycardia , Palpitations, hot flashes, arrhythmia , High blood pressure, deterioration in hypertension ;
• thrombocytopenia . ecchymosis . anemia .

Rarely observed:

• confusion;
• bullous rash, angioedema ;
• increase in liver enzymes, intestinal perforation, ulceration of the esophagus;
• duodenal ulcer and stomach ;
• myocardial infarction . ischemic stroke , The occurrence of congestive Heart Failure .

Kapsluly Celebrex: instructions for use (method and dosage)

According to the instructions on the use of Celebrex, a drug must be taken with 200 mg twice daily. It is necessary to select the lowest effective dose and a short course of treatment.

When familial adenomatous polyposis   the drug is taken as an additional means of 400 milligrams twice daily.

In acute pain   - First from 400 to 600 milligrams per day, then 200 mg twice a day.

When ankylosing spondylitis   - 100 milligrams twice daily. Maximum - 400 milligrams per day.

At rheumatoid arthritis   - From 200 to 400 milligrams per day dose divided into two steps. The maximum dose - 800 milligrams per day.

If the patient has a decrease in liver function, the dose should be reduced by half.

Overdose

In case of overdose should be taken to eliminate the drug and spend symptomatic therapy.

Cooperation

Do not use this drug in conjunction with other drives NPSV which do not contain acetylsalicylic acid .

Since the drug has no effect on the antiplatelet effects acetylsalicylic acid He is not seen as a replacement for its prevention of cardiovascular diseases.

Do not interact with the tolbutamidom . phenytoin . glibenclamide . Methotrexate . omeprazole   and antacids . At the same time taking celecoxib and lithium marked increase in the concentration of plasma second at 17 percent.

Terms of sale

The drug is available only by prescription.

Storage conditions

Keep the medication you need in a dry place at a temperature of 15 to 30 degrees.

Shelf life

Shelf life is three years.

Analogs of Celebrex

Analogs of the drug:

• Artoksib ;
• Zitsel ;
• Ranseleks ;
• Revmoksib ;
• Celecoxib .

Price counterparts Celebrex is a bit cheaper.

Reviews of Celebrex

According to the reviews of Celebrex on the forums, the drug is very effective, but also reviews of patients with evidence of numerous adverse events of drugs.

Price Celebrex where to buy

200 milligrams of Celebrex price in Russia is on average 400 rubles (10 capsules).

In Ukraine, the cost of the drug is an average of 220 hryvnia.

Price per pill Celebrex 3 blisters in the package is in the range of 1000-1100 rubles.