Description overdue on 26.09.2011

Citramon   - Combined preparation: acetylsalicylic acid   (ACK) + paracetamol   + caffeine . Non-narcotic analgesic drug. It has antipyretic, analgesic, psychostimulant effects. ASA belongs to the group of NSAIDs. Paracetamol affects the thermoregulatory center of the hypothalamus, providing pronounced antipyretic effect, inhibits the synthesis of prostaglandins . Caffeine stimulates vasomotor center, respiratory center, the reflex excitability of the spinal cord, expanding the lumen of blood vessels, relieves fatigue, reduces sleepiness, increases the ability to work (mental and physical). Dosage Form: Tablet. Citramon prescribed for pain syndrome   (toothache, headache, muscle, joint pain). The drug is effective in SARS , Fever, chills.

Contraindications:

Hemophilia allergic to aspirin, high blood pressure, functional disorders of the renal system, ulcerative lesions of the gastrointestinal tract, diseases of the hematopoietic system, glaucoma . ischemia , Hyperactivity, bronchial asthma . pregnancy . Not recommended for children under 15 liters. With extreme caution: if gout , Liver disease, renal system.

Side effect:

In most cases, Citramon well tolerated.

Gastrointestinal tract : Dyspepsia, ulcerative lesions, gastralgia, gastrointestinal bleeding, renal failure, diarrhea , Liver failure.

Other : Allergies, headaches, visual disturbances, hearing hypocoagulation, thrombocytopenia, toxic epidermal necrolysis. Children - Reye's syndrome .

Overdose:

Taking the drug at high concentrations leads to dizziness, drowsiness, confusion, lethargy, loss of consciousness, convulsions, difficulty breathing (bronchospasm), bleeding. Treatment: gastric lavage, followed by a reception adsorbents, symptomatic therapy.

Special instructions:

Children do not prescribe drugs, as part of which contains ASA (Prevention of Reye's syndrome: vomiting, hepatomegaly . acute encephalopathy ). Chronic administration is necessary to control the state of the hepatic system, peripheral blood. The risk of bleeding in the gastrointestinal tract, liver toxicity increases while receiving alcohol and drug Citramon. In the low-dose ASA reduces the excretion of uric acid from the body, which should be considered in patients with gout. ASA has teratogenecity . Citramon during pregnancy does not apply: in the first trimester is marked splitting of the upper sky, in the third trimester labors braked, the ductus arteriosus closes fetus, pulmonary vessels giperplaziruyutsya. The drug is excreted in breast milk, increasing the risk of platelet function disorders, bleeding in the development of the baby. Before elective surgery is recommended to refuse to accept tsitramon to prevent bleeding. In emergency situations it is necessary to inform your doctor about taking the drug.

Drug Interactions:

Citramon enhances the action reserpine , Indirect anticoagulants, gipoglikemichskih drugs, steroid hormones, Heparin . Reduces the effectiveness of furosemide . spironolactone , Protivopodagricakih, antihypertensive drugs. The drug increases the severity of side effects from taking Methotrexate NSAIDs, sulfonylureas , SCS. It is not recommended to combine with barbiturates . rifampicin . zidovudine , Antiepileptic drugs, ethanol   (increased hepatotoxic effects ).