Description overdue on 11/04/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications Ibuklina
• Contraindications
• Side effects
• Instructions for use Ibuklina (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Synonyms
• Babies
• With alcohol
• With antibiotics
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

The preparation includes the active substances Ibuprofen   (400 mg) and paracetamol (325 mg), and the following excipients: corn starch . MCC . sodium carboxymethyl starch (type A) . glycerol . talc . colloidal silicon dioxide . magnesium stearate .

Product form

Available in the form of tablets kapsulovidnyh orange film-coated on one side of the shell - mark. Permissible marbling coloring. The tablets are packaged in blisters on 10 pcs., Sold in cartons of 10 and 20 pieces.

Junior Ibuklin   Children - soluble tablets round shape with the risks of pink color, with splashes. Have a mint flavor.

Pharmacological action

The preparation has a combined composition, its effect is due to the action of the components.

Ibuprofen   It has on the anti-inflammatory, analgesic, antipyretic effects. Under its influence, it reduces the amount of prostaglandins in the inflammatory focus, and in healthy tissue. This action is caused by depression cyclooxygenase , A metabolic disorder arachidonic acid . Also suppressed exudative and proliferative phase of the inflammatory process.

Paracetamol   It provides indiscriminately blocking COX, has little effect on the gastrointestinal mucosa and in the water-salt metabolism. Provides antipyretic effects and pain relief.

The effectiveness of the combination effect of the components more pronounced than individually.

The drug helps to reduce arthralgia at rest and in motion, reduces the feeling of morning stiffness and swelling of joints, increases range of motion.

Pharmacodynamics and pharmacokinetics

Ibuprofen   almost completely and very rapidly absorbed from the gastrointestinal tract. The maximum concentration after oral administration occurs after 1-2 hours. Communication with plasma proteins is greater than 90%. Ibuprofen is slowly absorbed into the joint cavity, creating a concentration in synovial fluid than in blood plasma. Susceptible to metabolism. 90% s body is derived through the kidneys, a lower portion of output in the form of metabolites and their conjugates with bile.

Paracetamol   quickly adsorbed, its relation to plasma proteins is less than 10%, with an overdose of it increases slightly. The maximum concentration occurs after 0, 5-2 hours. In body fluids, paracetamol is distributed relatively evenly.

90-95% of the substance is metabolized in the liver. A minor part of hydroxylated microsomal enzymes. In breast milk gets a small amount of paracetamol - less than 1% of the dose.

Indications Ibuklina

Indications for use of the drug (from what Ibuklin tablets used for the symptomatic treatment):

• fevers Arising including due to colds or Flu ;
• attacks neuralgia ;
• myalgia ;
• pain of varying intensity in the back;
• joint pain, pain that occurs as a result of diseases of the musculoskeletal system;
• toothache;
• pain arising due to dislocations, sprains, fractures, bruises strong;
• painful menstruation ;
• postoperative pain or traumatic nature.

From what Ibuklin used in the treatment of children, the pediatrician will explain in more detail. It is to know exactly what the drug is used and how to help, because it can only relieve pain and inflammation in the period of use. The progress of the disease as a whole does not affect its use.

Contraindications

Contraindications for treatment Ibuklinom following:

• high level of sensitivity to the components that are part of the drug;
• acute form duodenal ulcer   or stomach ;
• bleeding   in the stomach or intestines;
• inflammation of the intestines;
• severe form renal failure , Progressive kidney disease;
• optic nerve damage;
• bronchial asthma . polyposis   nose and paranasal sinuses, combined with intolerance of aspirin and other NSAIDs;
• diseases of the circulatory system;
• liver disease or severe acute liver failure over;
• hyperkalemia ;
• III trimester of pregnancy.

Side effects

The drug can induce the occurrence of certain side effects when used for adults and children:

• The functions of the digestive tract Symptoms of NSAID-gastropathy (nausea, vomiting, heartburn , Epigastric pain, diarrhea ); less marked liver damage, erosion and ulcers, bleeding, pancreatitis , Dry mouth, constipation , Stomatitis.
• The functions of the nervous system : Increased anxiety, dizziness , Headache, agitation, depression, hallucinations ; less marked decrease in hearing, vision, double vision, aseptic meningitis, amblyopia.
• The functions of the cardiovascular system : Increased blood pressure, tachycardia , heart failure.
• The functions of blood : Thrombocytopenic purpura, anemia, thrombocytopenia, leukopenia.
• The functions of the respiratory system : Bronchospasm, breathlessness .
• The functions of the genitourinary system : Acute renal failure, edema, allergic nephritis, polyuria, cystitis .
• Occurrence   allergic reactions .
• Change laboratory parameters : Reduction of glucose levels, hematocrit, Hemoglobin ; increase the bleeding, increased liver transaminases.
• Heavy sweating.

If the temperature Ibuklin patient receives high doses over a long period, you may experience gastrointestinal ulcers, bleeding, vision problems. In this case it is necessary to visit a doctor to replace pills temperature to another drug.

Instructions for use Ibuklina (method and dosage)

Instructions on Ibuklin following: medication taken orally before meals or 2-3 hours after a meal. The tablets do not need to chew, washed down with plenty of water.

Adults need to take one tablet three times a day Ibuklina. Three tablets - is the maximum allowable dose. Between taking pills must be at least 4 hours. For the elderly and those who suffer from dysfunction of the kidneys and liver, the interval between doses tablets should be at least 8 hours.

Children who are 12 years of age and who have weight more than 40 kg, take a day 1 tablet 2 times.

Treatment Ibuklinom to reduce the temperature can last for more than three days. Use of the drug as a possible anesthetic for no more than five days. If you want to continue the therapy, you should first be sure to consult with your doctor.

Instructions for use of child Ibuklina following: one tablet of the drug Ibuklin Junior dissolved in one teaspoon of warm water. Dosage Ibuklin Junior for children is made depending on their weight.

• With a weight of 11-15 kg - 1 tablet 1 time in 8 hours 3 times a day;
• With a weight of 16-21 kg - 1 tablet 1 time per 6 hours, 4 times a day;
• With a weight of 22-40 kg - 2 tablets 1 time in 8 hours 3 times a day;
• Weighing more than 40 kg takes the minimum dose for adults.

Overdose

In case of overdose, you may experience the following symptoms:

• disorders of the gastrointestinal tract functions, accompanied nausea . vomiting . diarrhea , Pain in the epigastric region;
• bleeding Occurring after 12-48 hours;
• state of lethargy, depression . sleepiness ;
• headache;
• irregular heartbeat, drop in blood pressure;
• convulsions;
• disturbance of consciousness ;
• noise in ears.

If you suspect an overdose, you should immediately seek the help of doctors. In case of overdose gastric lavage is practiced during the first 4 hours after ingestion, the use of alkaline drinking Activated Carbon Holding   forced diuresis . Symptomatic treatment. Other therapies physician determines individually, depending on the concentration of components in the body Ibuklina.

Cooperation

Simultaneous treatment with drugs containing ibuprofen and acetylsalicylic acid Reduced anti-inflammatory and antiplatelet effect of the latter.

Wikipedia suggests that the interaction of the drug with Valium, ethanol, corticotropin increases the likelihood of developing erosions   and gastrointestinal ulcers .

Ibuprofen activates the effects on the body thrombolytic agents . direct and   anticoagulants . colchicine . antiplatelet agents . As a consequence, it increases the risk of bleeding complications. Also enhanced hypoglycemic effect insulin   and oral medicaments with hypoglycaemic effect.

When co-administered with diuretics, antihypertensive agents, and their effectiveness is reduced. The analgesic effect of ibuprofen increases caffeine. When you receive drugs of gold, cyclosporine nephrotoxicity of ibuprofen increased. At simultaneous reception antacids   and kolestiramina   decreases absorption Ibuklina.

Terms of sale

In pharmacies sold without a prescription.

Storage conditions

Store the product must be dry, in which the light beams do not fall. The temperature should not be greater than 25 ° C. The drug should be protected from children.

Shelf life

Store the drug can be 5 years.

Cautions

Abstract indicates that treatment should be carefully carried out at IBS, chronic heart failure, diabetes , Peripheral artery disease with a history of gastrointestinal ulcers, infections Helicobacter Pylori . cirrhosis . nephrotic syndrome . Also cautiously drug used to treat the elderly, smokers, those who regularly drink alcohol.

It is not necessary to simultaneously receive Ibuklin and other drugs that are a part of paracetamol, NSAIDs.

Analogs

In pharmacies sold Ibuklina analogs that contain similar components. It brustan . Ibuprom . Dolar . hayrumat   and others. Some analogues have a higher price than Ibuklin. The average price of analogues are from 70 to 120 rubles.

Synonyms

Brustan, Ibuklin Junior, Spondifen.

Babies

Ibuklin not indicated for the treatment of children under 12 years.

Ibuklin Junior is not appointed for children under three years of age.

With alcohol

If the patient simultaneously receives Ibuklin and alcoholic beverages increases the likelihood of hepatotoxicity . Therefore, during treatment with this drug should not take alcohol.

With antibiotics

Sometimes patients the question arises, Ibuklin - it antibiotic   or not. The answer is clear: this is not an antibiotic drug. If necessary, in parallel with the reception Ibuklina appointed by antibiotic therapy, but the complex treatment is carried out only under medical supervision.

During pregnancy and lactation

If you need to take when Ibuklin pregnancy   during breast-feeding , Necessarily clearly define the expected benefit from the treatment and the probable risk. In the first trimester of pregnancy, if necessary, possible short-term drug treatment. By briefly taking Ibuklina during lactation tend to stop feeding process is not necessary.

Reviews on Ibuklin

Reviews physicians and patients indicate that Ibuklin effectively lowers the body temperature and in adults and children. According to people who were taking the drug, he quickly relieves pain, has a strong antipyretic effects. Side effects are rare. Reading the reviews on Ibuklin children, it may be noted that most parents report as the occurrence of side effects in children loose stool, pain in the abdomen.

However, Ibuklin for children is a very popular and effective drug. Responses indicate that it may be given to children who have an increased body temperature do not impair the other drugs. If you observe the correct dosage for children, the drug has an effect faster and more pronounced than the other syrup or tablets.

Price Ibuklin where to buy

The cost of the drug in pharmacies Russia is on average from 80 to 100 rubles. (10 tablets). Tablets Ibuklin in Ukraine will cost 27-30 USD. How much does the drug depends on the number of blisters in a pack. The price for children Ibuklin practically does not differ from the price of medicines for adults. In Russia, the price of Ibuklin Junior is an average of 80 rubles.