Description overdue on 04/15/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications Katadolona
• Contraindications
• Side effects
• Instructions for use Katadolona (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Synonyms
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

In one capsule of the drug is contained flupirtine maleate   + 100 mg Excipients ( gelatin, water, E172, sodium lauryl sulfate, titanium dioxide, silica, magnesium stearate, copovidone, calcium hydrogen phosphate dihydrate ).

One tablet Katadolon Forte   and Katadolon Retard : 400 mg of flupirtine maleate + auxiliaries.

Product form

Description Katadolona: capsule shell made of gelatin, solid red powder contents yellow or green-yellow tints. Cardboard boxes 30, 10 and 50 tablets.

Katadolon Forte   - Yellow tablets, biconvex may contain various inclusions of oval on one side of risk. Blisters on 7, 10 and 14 units.

Katadolon Retard   - A capsule shell made of gelatin, red. Packages 30, 10 or 50 pieces.

Pharmacological action

Analgesic Having antispasmodic   action.

Pharmacodynamics and pharmacokinetics

The drug is non-opioid analgesics . It has a central action. Not addictive. Affects regulatory G-protein Altering the potential difference Calcium channels Thereby stabilizing the membrane potential of neurons.

At doses not exceeding the maximum allowed, the matter does not affect the M- and H-cholinergic receptors . dopamine, opioid, serotonin   and alpha 1 and alpha 2-adrenergic receptors .

Analgesia occurs at the expense disclosure of of potassium channels in nerve cells. The drug affects the NMDA-receptors and thereby stops the current through the calcium ions semipermeable   the membrane wall. Flupirtine does not respond to nerve impulse received nociceptive stimuli Thereby obezbolivaya. The drug gets newly emerged pain, giving them " inflates "And develop into chronic. The tool is effective in reducing chronic pain have been set.

Miorelaxation It is due to blocking motto- and intermediate neurons.

The drug has the property to protect neurons from the toxic effects. Activating calcium channels, thereby reducing agent content destructive calcium ions in the cell.

When entering the gastrointestinal tract 90% of the drug is completely absorbed. 75% of the dose is undergoing a process of metabolism   in the liver.

The half-life of the organism is 7 hours. In Katadolona Forte   and Retard - 15 hours (due to the slow stepwise release of active substance). Up to 70% is excreted by the kidneys, and the rest - through the intestine (feces and bile). Older patients and those with abnormalities in the kidneys and liver, the period of withdrawal from the body is increased.

Indications Katadolona

The indications for use of the drug are the pains of different origins caused by spasms   smooth muscle.

From what Katadolon pills? Postoperative and headaches, neck and back, with malignancies   and tumors, etc.

Contraindications

The drug is not recommended for hypoalbuminemia , Liver and kidney diseases, allergies   to the active substance or auxiliary components, ringing in the ears, in the treatment of children and the elderly and Alcoholics .

Side effects

Often manifested fatigue dizziness , Weakness, at least - nausea, flatulence, abdominal pain and indigestion, tremors, headache, anxiety .

Rarely, very rarely occur in patients allergic reactions, visual impairment, drug-induced hepatitis . Adverse reactions may disappear in the course of the preparation.

Instructions for use Katadolona (method and dosage)

Orally . Regardless of the meal. The duration of treatment and the dosage prescribed by the physician, depending on the disease and its flow. Max flupirtine   per day - 600 mg.

Adults: 3-4 tablets per day, at regular intervals. With a very strong pain can increase the dose to 200 mg, but not exceeding the daily maximum. For patients older than 65, with kidney or gipoalbunemii   lekarstva- daily dose of 300 mg, with liver disease - 200 mg.

Instructions on Katadolon Forte and Katadolon Retard

The drug is administered one tablet (0 4 g) per day until the disappearance of pain syndrome.

Overdose

There confusion, tachycardia, nausea, dry mucous membranes . In case of overdose - gastric lavage and treatment of, according to manifested symptoms.

Cooperation

Together with the admission warfarin and diazepam , Due to the fact that these drugs bind to proteins flupirtine It can be vytesenen out of the cage and the action of PM may increase.

Muscle relaxants, sedatives and ethanol   increasing their exposure under the influence of drugs.

Do not combine with   carbamazepine, paracetamol and flupirtine . It is necessary to monitor the prothrombin index   while admission to coumarin .

Terms of sale

It requires a prescription.

Storage conditions

The cool, dark place (15 to 25 degrees). Keep out of the reach of children.

Shelf life

Katadolon - 5 years.

Katadolon Forte and Retard - up to 2-x years.

Cautions

Use caution when taking the drug and management mechanisms, as the drug can reduce the rate of reaction and visual acuity. Flupirtine can stain urine a greenish color.

Analogs Katadolona

Analogues Katadolona Forte Katadolona and Katadolona Retard are: Acupan, milistan, nefopam, sinmeton . Price analogs are generally lower than the originals.

Synonyms

Flugesik .

During pregnancy and lactation

Not applicable.

Reviews on Katadolon

Katadolon Retard relieves painful syndrome quickly and a long time. Although the incidence of adverse effects, some addicts use the drug for pain relief during withdrawal .

Many people write good reviews on Katadolon forte 400 mg. The drug is effective in reducing pain, but often appear dizziness and general weakness.

Reviews of doctors : The drug is well and rapidly analgesic, used in surgical practice. It does not cause addiction. However, it is quite a powerful tool, so take the drug without a prescription is not necessary.

Price Katadolon where to buy

Price Katadolona Forte 400 mg - 1150 rubles per 14 pieces. Price tablets Katadolon Retard in the last 7 tablets amounts to 926 rubles. Buy 10 capsules of the drug will cost 429 rubles.