Description overdue on 07/11/2013

The analgesic, antipyretic a means of . Active component - paracetamol. The mechanism of action is aimed at reducing the excitability of the central field (located in the hypothalamus) for inhibition of prostaglandin. Active ingredient reduces body temperature when feverish syndrome, reduces the severity of pain by inhibiting prostaglandins and blocking the enzyme   cyclooxygenase . Unlike hypothermic Tsefekon medication does not affect the normal body temperature. Anti-inflammatory effect of the drug is weak in view of blocking the active substance cellular peroxidases in peripheral tissues located. The application does not affect the Tsefekona water and salt exchange   in the body. The current component does not irritate the mucous membranes of the digestive tract wall. Active substance sufficiently rapidly reaches the systemic circulation, and passes through the blood-brain barrier. Metabolites are renal system without causing adverse effects on the liver. Tsefekon for children available in the form of suppositories (rectal forms).

Indications:

Candles Tsefekon prescribed for relief   fever Caused by infectious diseases or the administration of the vaccine. The drug is used for muscle pain, toothache, migraine , Relief for injury pain . Candles Tsefekon children are recommended for use for the relief of fever after vaccination. The drug can be administered to children from 1 month of age.

Contraindications:

The drug is not prescribed for rectal bleeding. Instructions for use Tsefekona discourages the use of candles in the presence of inflammation in the anus and rectum. The drug is contraindicated in case of hypersensitivity to paracetamol. When thrombocytopenia, with liver disease, functional disorders of the renal system, anemia candles Tsefekon prescribed with caution in consultation with experts.

Side effects, overdose:

Reviews on Tsefekon point to its good tolerability. In rare, isolated cases occur side effects. Hematopoietic system: agranulocytosis , Thrombocytopenia (decrease in the number of platelet cells), leukopenia, anemia. The digestive tract:   epigastric pain, diarrhea, vomiting, nausea. Allergic responses as angioedema, rash on the skin and mucous walls, urticaria. Long-term therapy may lead to functional disorders of the renal system. Overdose cases are not registered.

Mode of application:

Candles Tsefekon apply only rectally. Before using the drug is recommended to clean the rectum by spontaneous bowel movements or by enema. Tsefekon dosed for children under the scheme, depending on the age of the child. The daily dosage of - not more than 60 mg / kg body weight. For achievement analgesic effect   medication prescribed for 5 days for relief pain   - for 3 days. Adjustment of the treatment regimen and dosing of the drug carries a doctor. After the introduction of a suppository recommends that you keep a horizontal position for at least 30-40 minutes.

Special instructions:

Candles Tsefekon D produced in a carton (10 suppositories). When pain or itching in the anus, rectum and administered medication overturned warm sunflower oil (1 tablespoon) into the anus. Tsefekon children can be used only under the supervision of parents, adults. Price Tsefekona - up to 100 rubles.

Drug Interactions:

Hepatotoxic effect increases in the treatment of inhibitors of microsomal oxidation. Manifestation nephrotoxic effects   increases with concurrent therapy salicylates. Tsefekon improves medication with anticoagulant effect. Toxicity increases when receiving chloramphenicol. Medicines with severe hepatotoxic effects can lead to an overdose of paracetamol because of lower metabolic rate.