Description overdue on 07/10/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications askofen
• During pregnancy (and lactation)
• Contraindications
• Side effects
• Tablets askofen, instructions for use (method and dosage)
• Overdose
• Cooperation
• Cautions
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• With alcohol
• Reviews
• Price, where to buy

Composition askofen-P

Each tablet contains the active ingredients with the composition: paracetamol   200 mg acetylsalicylic acid   200 mg caffeine   40 mg.

Excipients: stearic acid, povidone, potato starch, talc, calcium stearate, silicone emulsion   and vaseline oil.

Product form

Available askofen-P in the form of tablets lighter shade, Valium forms without any special smell. Over the counter medications sold in packs of 10 pieces.

Pharmacological action

The drug has a combined effect, uniting   nonsteroidal anti-inflammatory, non-narcotic analgesic   and   inducing effect.

Pharmacodynamics and pharmacokinetics

Combination drug efficacy which provide its components.

Acetylsalicylic acid   has a significant analgesic, antipyretic   and   anti-inflammatory   action inhibits platelet aggregation .

Paracetamol   also exhibits antipyretic   and anesthetic effect.

Caffeine   improves reflex excitability of the spinal cord,   excitation of the respiratory and vasomotor functions, vasodilation , Muscle, heart, brain, kidneys, reducing platelet aggregation . Furthermore, reception caffeine helps reduce drowsiness and fatigue, improve efficiency and so on.

As a result of ingestion absorbed about 90% of the drug. The maximum substance concentration in serum obtained at various times: paracetamol - In one hour, caffeine   - 2, 5 hours, acetylsalicylic acid   - 1-2 hours.

Because almost 80% of the body's acid active substances derived using kidneys.

Indications askofen

• moderate pain of various etiologies, such as: headache   or toothache .   migraine, neuralgia, myalgia, arthralgia   and so on;
• fevers Caused by colds   and rheumatic diseases .

Askofen-P during pregnancy

It should be noted that this drug is not recommended for acceptance during pregnancy, especially in the I and III trimester. It allowed a one-time use of drugs in the 2nd trimester of pregnancy, but if it is well established that it will not cause harm to the fetus.

It is known that taking the drug in the I trimester can cause fetal malformations in the form splitting of the upper palate Caused by a teratogenic effect acetylsalicylic acid.

In the III trimester - there is likely inhibition of labor, closure of the ductus arteriosus   the unborn child, causing hyperplasia of the blood vessels in the lungs   and hypertension, vascular circulation.

Contraindications

• intolerance to the drug or its components;
• various gastrointestinal lesions;
• irregularities in the liver or kidney;
• deviations in the activity of the respiratory system such as asthma;
• dissecting aortic aneurysm;
• some disorders of the nervous and cardiovascular systems;
• age less than 15 years;
• lactation . pregnancy   and so on.

Side effects

In the treatment with this drug may experience a variety of problems in the activity of the gastrointestinal tract in the form of: anorexia, nausea, vomiting, gastralgia, diarrhea, erosive and ulcerative lesions, bleeding.   It is also possible the development of: hepatic or renal insufficiency, tachycardia   and increase in blood pressure.

The long reception drug causes: dizziness , noise in ears, Headache . hypocoagulation . a variety of adverse syndromes and disorders of the liver .

Tablets askofen, instructions for use (method and dosage)

As indicated by the instructions for use askofen-P, the tablets prescribed for admission after eating 2-3 times a day in an amount of 1-2 pieces. The maximum daily dosage should not exceed 6 pieces, and the rest to be less than 4 hours.

Given the indications for use askofen, you need to follow some features Reception:

• drink milk is better tablets, normal or warm mineral water;
• patients with impaired renal or hepatic function is necessary to increase the interval between taking the medicine - 6 hours.

In addition, the rate of analgesic therapy should not exceed 5 days and treatment of heat - more than 3 days. In other cases, the duration of treatment and dosage is determined by the doctor.

Overdose

In case of overdose can occur:

• nausea, vomiting, pain in the gastrointestinal tract;
• sweating, pale skin;
• tachycardia;
• ringing in the ears;
• drowsiness, collapse, convulsive state;
• bronchospasm,   respiratory problems and so on.

If there is a suspicion poisoning , The urgent need to bring medical assistance. Typically, the victim was washed stomach and appoint adsorbents.

Cooperation

Simultaneous treatment with askofen-P leads to increased action Heparin . reserpine, anticoagulants Steroid hormone   and some   hypoglycemic agents . It is also likely to decrease the effectiveness of furosemide, spironolactone . antihypertensive   and   protivopodagricakih drugs That helps to excrete uric acid from the body.

Noting the increasing side effects glucocorticosteroids . Methotrexate Derivatives sulfonylureas And nonsteroidal anti-inflammatory drugs, and narcotic analgesics.

It is not recommended to combine this drug with barbiturates , Antiepileptic drugs, zidovudine, rifampicin and spirituous beverages, because still a possibility of hepatotoxic effect.

Influence of paracetamol increases the period of breeding chloramphenicol   almost 5 times. With regard to caffeine, it accelerates the suction ergotamine.

Combination therapy with Salicylamides   and other stimulants microsomal oxidation contribute to the production of toxic metabolites paracetamol Adversely affecting the function of the liver.

Simultaneous treatment with Metoclopramide   increases the absorption paracetamol . Repeated use can enhance the effect of anticoagulants.

Cautions

Long-term treatment with this drug requires monitoring of peripheral blood and liver function.

Acetylsalicylic acid   antiagregatnym action has, for this reason, patients prior to surgery should immediately warn doctors that they are taking this medication. Low dose acetylsalicylic acid reduces the excretion of uric acid, which often provoke an attack of gout.

Terms of sale

These pills without a prescription.

Storage conditions

The medicine should be stored in a relatively dry and dark place at a temperature of 25 ° C.

Shelf life

The product is fit for 2 years.

Analogs

Such actions also possess drugs: Oraphim, flexo, Diklovit, Artrozilen, Bofen   and others.

Alcohol and askofen-P

In the treatment with this drug is prohibited the use of any alcoholic beverages because they increase the risk of bleeding in the gastrointestinal tract.

Reviews askofen-P

As numerous patient testimonials left in various forums, the drug is an excellent, low-cost and effective means of combination. Many users take long askofen tablet, from which the therapeutic effect does not become lower as they use them periodically.

However, some patients ask, from what askofen-P makes it best and how often can I use it? At this experts respond that the tablets have equivalent analgesic, antipyretic and anti-inflammatory action. However, when these undesirable symptoms are not eliminated quickly, then you need to see a doctor.

In addition, there are many features and contraindications to the reception of the drug. For example, Askofen Darnitsya   capable of more than other forms of expression aggravate asthma, causing the development of a severe allergic reaction.

Askofen raises or lowers the pressure?

This preparation often takes people suffering hypotension That is, a reduced pressure to get rid of this disease. However, they argue that such treatment was recommended by a doctor named. Most patients are satisfied with the effect produced.

Of course, this combination of materials include low dosage   caffeine Not able to have a stimulating effect on the central nervous system, but it normalizes the tone of blood vessels of the brain and accelerates blood flow. Therefore, patients with high blood pressure need to take care of these pills, and people with low blood pressure still do not abuse such a therapy.

Price askofen-P, where to buy

This medication is available to virtually all patients, as in the Russian drugstores, its price is 14 rubles.