Description overdue on 07/29/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications Revalgina
• Contraindications
• Side effects
• Instructions for use Revalgina
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Reviews
• Price, where to buy

Composition

One tablet Revalgina   contains:

• fenpiveriniya bromide - 0, 02 mg;
• Metamizole   - 500 mg;
• pitofenone hydrochloride   - 2 mg.

Additional components: corn starch . lactose anhydrous . microcrystalline cellulose, magnesium stearate . silica . talc .

The composition 1 ml Injection Solution   includes:

• Metamizole   - 500 mg;
• pitofenone hydrochloride   - 2 mg;
• fenpiveriniya bromide   - 0, 02 mg.
• additional components.

Product form

White pills: flat, round, with a dividing strip and cut edges. Has a plate 10 pieces. Packed in cardboard boxes on the 2 or 10 plates.

Injection:

• 2 ml ampules   in blister, five vials in a carton box.
• Ampoules of 5 ml   in blister 5 pieces. Carton packs of 5 or 25 vials.

Pharmacological action

Non-narcotic analgesic, antispasmodic agent.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Revalgin is a combined analgesic and antispasmodic agent. He contains: pitofenone hydrochloride . Metamizole   and fenpiveriniya bromide . The process of drug action is based on the pharmacological properties of the active ingredients.

Pitofenone   is an antispasmodic, rendering bright myotropic action similar to papaverine . Pitofenone lowers elevated the tone of the smooth muscle layers of internal organs, eliminates spasms, has analgesic effects in spastic pain.

Metamizole - A non-steroidal anti-inflammatory agent, which is based pyrazolone . Metamizole has anti-inflammatory, antipyretic, analgesic effect, thereby reducing synthesis of pro-inflammatory cytokines . This in turn leads to an intensive reducing inflammation.

Fenpiveriniya bromide It is holinoblokatorov . Due to anticholinergic process, a layer of smooth muscle of the internal organs relaxes.

All active substances Revalgina potentiate each other, thereby enhancing the effect of the drug.

Pharmacokinetics

Metamizol Partly sodium binds to blood proteins, the process of metabolism in the liver and excreted in the urine in the form metabolites .

Indications Revalgina

Revalgin as a solution or tablets assigned patients whose pain accompanied by spasms of the smooth muscle layer of the internal organs. The drug is indicated for:

• hepatic, renal colic ;
• bladder spasm ;
• stomach   and   intestinal colic ;
• spastic dysmenorrhea ;
• biliary dyskinesia .

The drug relieves pain syndromes neuralgia, sciatica   and arthralgia . Revalgin also appointed as an adjuvant analgesic character after surgery and diagnostic procedures. The tablets can be administered in infectious and inflammatory processes, and elevated temperature.

In addition, the indications for use of injections involved with the Revalgina migraine pain . myalgia and headache.

Contraindications

Revalgin as solution   and tablets   not given to patients with individual intolerance to the active ingredients of the drug and other components pyrazolone .

The drug is not administered in the following cases:

• severe disorders of the liver, kidneys;
• acute hepatic porphyria ;
• gastrointestinal obstruction ;
• prostatic hypertrophy ;
• angle-closure glaucoma ;
• atony gall   or Bladder ;
• urinary retention ;
• development bronchospasm ;
• dysfunction of hematopoiesis;
• during Lactation .

With caution must be exercised in the appointment of the drug in cases of liver and kidney disease stage light, diseases of the stomach, coronary heart disease   and chronic forms Heart Failure .

Side effects

Overall, the drug was well tolerated by patients. Side effects were observed in cases of increased dosage or reception Revalgina more than three consecutive days. At the same time, the destabilization of the digestive system, exacerbation gastritis , Dry mouth, worsening stomach ulcer , Violations of the chair.

Central nervous system   reacts headache . ccomodation , Reduced visual acuity, dizziness .

AT Cardiovascular system   can be traced unstable heart rate and hypotension .

Issues Urinary Tract   manifested in the kidney function, difficult urination, oliguria . staining urine red .

AT circulatory system   may develop anemia . granulocytopenia . agranulocytosis , Symptoms Hyperthermia , a sore throat, vaginitis . stomatitis . proctitis   and chills .

Among occur following allergic reactions : bronchospasm . hives . Lyell's syndrome . Stevens-Johnson syndrome . anaphylactic shock   and angioedema .

Instructions for use Revalgina

Application solution for injection

Revalgin used parenterally as intramuscularly or intravenously. Before injecting the muscle, the ampule with a solution need to warm to body temperature. Intramuscular medication is administered in the gluteal region. In this therapeutic effect occurs within 20-30 minutes.

When administered intravenously, the drug should be administered slowly. The introduction rate - 1 ml for 1 minute. It is necessary to control arterial pressure Breathing and heart rate. The duration of the course of injections and dosage appoint a specialist.

Instructions for use tablets Revalgin

Revalgin designed for oral use. Drug in tablet form is best taken after eating drinking waters. The duration and dosage indicates the doctor for each patient individually. Typically assigned one or two tablets throughout the day. The maximum duration of the course is three days.

Overdose

With an overdose of the drug can be observed:

• ccomodation ;
• dry mouth ;
• confusion ;
• convulsions ;
• disruption of the liver and kidneys.

In case of overdose symptomatic therapy. Washed stomach, appoint enterosorbentnye and saline laxatives. Not excluded hemodialysis   and forced diuresis .

Cooperation

It is strictly forbidden to mix the drug ethanol .

Revalgin not used in conjunction with other groups of non-narcotic analgesics, to avoid manifestations toxicity .

Antidepressants   and oral contraceptives   Metamizolum slow down the metabolism in the liver and raise the risk toxemia .

Barbiturates and other inductors significantly weaken the value of metamizol.

Tranquilizers   and sedatives enhance the analgesic effect of the drug. If necessary, at the same time receiving drugs with Revalginom, should consult a physician.

Terms of sale

Sold without prescription.

Storage conditions

Revalgin stored at a temperature range - 15 - 25 ° C. Keep out of the reach of children.

Shelf life

Shelf life is Revalgin - 3 years.

Cautions

By the use of the drug, should be approached with extreme caution in patients with impaired renal function and liver suffering hypotension Sensitive non-narcotic analgesics and NSAIDs.

Prolonged use is necessary to control the overall state of the peripheral blood and liver.

Analogs

• Baralgin
• Maksigan
• Baralgetas
• Spazmalgon
• Spazmalin
• Spazgan

Reviews Revalgine

Reviews about the drug have a positive character. Frequently asked question " From what Revalgin? "I found a lot of answers in a review of patients treated with this agent. Some truck drivers take to the road Revalgin, it helps them when "Professional" pain in the neck . Others find the drug as an effective remedy migraine . toothache And some of the girls are taking it in the critical days for pain relief.

From what pills Revalgin more help? The best answer - consult with a doctor, and it will determine your need for individual reception.

Price Revalgina where to buy?

Average price Revalgina tablets   in the Moscow region: the tablet №20 - from 60 to 75 rubles, tablets №100 - 155 -190 rubles.

Cost Revalgina ampoules : 5 ml ampoules №5 - 80-90 rubles.