Description overdue on 03/27/2013

Combined preparation. The drug is Non-narcotic analgesics . Included in the Tsitrapara ingredients: paracetamol, acetylsalicylic acid, caffeine . anti-inflammatory effect , Has antipyretic and analgesic effects. Paracetamol is inhibited during the process of synthesizing prostaglandins in peripherally spaced tissues influences heat regulating center Which is located in the hypothalamus. Caffeine expanding the lumen of blood vessels to the heart muscle, kidney tissue, brain, skeletal muscle; increases physical and mental performance and activity; component has a stimulating effect on vasomotor and respiratory centers, increases the excitability of the spinal cord at the level of reflex. Contained in the product is not the amount of caffeine stimulates the central nervous system, but the blood flow accelerates and normalizes vascular tone in the brain. Aspirin improves   microcirculation   in inflammatory foci, inhibits thrombosis   and the process of platelet aggregation, reduces the severity of pain caused by inflammation; Tsitrapar available in tablet form and in the form of granules.

Indications:

Drug Usage Tsitrapar recommends prescribers for relief pain   various origins (mild to moderate severity): Neuralgia, toothache, headache,   arthralgia , Myalgia. Tsitrapar prescribed for feverish syndrome on the background influenza and acute respiratory disease .

Contraindications:

Tsitrapar not prescribed for gipoprotrombinemii , Erosive and ulcerative lesions of the digestive system (severe acute phase), when carrying a pregnancy, vitamin deficiency K, portal hypertension, "Aspirin" triad , Gastrointestinal bleeding, breast-feeding, severe kidney disease system, sleep disorders, elevated anxiety, lack of glucose-6-phosphate dehydrogenase, hemorrhagic diathesis , Severe arterial hypertension, glaucoma, severe coronary artery disease after surgery. In the pathology of the liver and gout Tsitrapar prescribed with caution, after prior consultation of experts. The drug is not prescribed for children until the age of 15 because of the risk of Reye's syndrome on the background of a viral infection, followed by hyperthermia . In the pathology of the liver and gout Tsitrapar prescribed with caution, after prior consultation of experts.

Side effect:

Erosive and ulcerative lesions of the digestive system, nephrotoxicity , Gastralgia, hepatotoxicity, nausea, vomiting, increased blood pressure, tachycardia, bronchospasm, allergic responses. Long-term drug therapy can cause Tsitrapar hemorrhagic syndrome   (purpura, bleeding from the gums, nosebleeds and other symptoms), dizziness, headaches, disturbances of vision, tinnitus, hypocoagulation , Decrease platelet aggregation, loss of kidney tissue with the formation of papillary necrosis, toxic epidermal necrolysis , Deafness, Reye's syndrome in children (manifested by dizziness, nausea, vomiting, drowsiness, lethargy, hyperpyrexia, disturbances in the kidney system, disorders of the psyche and the nervous system), malignant exudative erythema .

Overdose:

It appears lethargy, nausea, dizziness, collapse , Drowsiness, bronchospasm, seizures, vomiting, bleeding, anuriei , Shortness of breath. Against the background of the central pulmonary hyperventilation system develops respiratory alkalosis   (sweating, cyanosis, suffocation carbon dioxide acidosis . It requires dynamic monitoring of the electrolyte balance, CBS; necessary to introduce sodium lactate, sodium citrate, sodium hydrogen carbonate.

Mode of application:

Tsitrapar taken during a meal. Driving: every 4 hours 1 tablet. The average daily dosage is 3-4 tablets, maximum - 8 tablets. Relief of pain - 1-2 tablets. Correction doses Tsitrapar carried out by the attending physician.

Special instructions:

Tsitrapar not indicated for children, as virus infection increases the risk of medication Reye's syndrome   (enlargement of the liver, acute encephalopathy, prolonged vomiting). Long-term treatment requires mandatory monitoring of the state of the liver and peripheral blood. Part of the drug acetylsalicylic acid slows clotting So before surgery is mandatory to inform your doctor about taking medication. Patients with wheeze reactions , Hypersensitivity to the Tsitapar appoint, subject to safeguards (the possibility of an emergency). Aspirin exerts teratogenecity , Is excreted in breast milk (the risk of bleeding in infants due to dysfunction of platelets). Treatment requires a complete rejection of receiving alcoholic beverages (increased risk of gastrointestinal bleeding).

Drug Interactions:

Tsitapar able to enhance the effect of Steroid hormone anticoagulants , Heparin. Risk of side effects increases significantly in the treatment of Methotrexate   and other medicines NSAIDs group. Tsitapar reduces the effectiveness of antihypertensive drugs, furosemide, spironolactone, protivopodagricakih drugs. Stimulants microsomal oxidation, salicylamide, rifampicin, antiepileptics, barbiturates cause the formation of toxic metabolites paratsematola that have a negative impact on the functioning of the liver. Under the influence metoclopramide   accelerating the process of absorption of paracetamol. The drug increases the excretion of chloramphenicol 5 times. Suction ergotamine accelerated by caffeine.