Description overdue on 04/09/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications Ultrakain DS
• Contraindications
• During pregnancy (and lactation)
• Side effects
• Instructions on Ultrakain D-C (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• With alcohol
• Reviews
• Price, where to buy

Composition

The preparations contain the active substance: 40 mg / ml Articaine hydrochloride   and 6 mg / ml epinephrine hydrochloride.

As auxiliary components are used: bisulfite and sodium chloride , Water for injections.

Product form

Produced articaine D-C in the form of ampoules of 2 ml volume in a single package - 100 vials, cartridges and special volume 1, 7 mL, in the same package - 100 pieces. The drug solution is completely transparent, it does not have any foreign smell and impurities.

Pharmacological action

Ultrakain D-C has a local-anesthetic effect.

Pharmacodynamics and pharmacokinetics

This drug - Local anesthetic Which is actively used in dentistry for infiltration and conduction anesthesia. Its use allows you to block membrane depolarization of nerve endings, thus significantly reduced the perception of stimuli and nerve impulse. Effect of the drug quickly enough, and is usually 1-3 minutes. Duration of anesthesia persists average 45 min.

Low content   epinephrine   in this preparation indicates that the possible effects on the cardiovascular system is very low, with little or no increase in blood pressure and heart rate.

In the body, the active components of the preparation, namely articaine , Binds to plasma proteins by 95%. The maximum concentration of an injection under the mucous membrane of the oral cavity is achieved within 25 min. It was found that the minimum amount of the drug crosses the placental barrier, little is excreted in breast milk. Withdrawal artikaina   It is predominantly excreted through the kidneys.

Indications Ultrakain DS

This drug is used for:

• not complicated by multiple or single tooth extraction;
• Tooth preparation for setting crown;
• tooth cavity preparation to therapeutic interventions;
• other standard dental work, such as common serious diseases.

Contraindications

This drug is not used for patients who are allergic to articaine, epinephrine   or other components of its components. In addition, the articaine is contraindicated in:

• tachyarrhythmias   and tachycardia;
• angle-closure glaucoma;
• pheochromocytoma;
• hyperthyroidism;
• asthma;
• acute cardiovascular insufficiency;
• expressly hypertension   and so on.

Ultrakain DS in pregnancy and lactation

It is believed that the application of the local anesthetic has a non-stress exposure, providing adequate anesthesia for various operations, including in dentistry. Through the blood-placenta barrier gets a small amount artikaina So it can be used in pregnancy .

Once in the body, atrikaina hydrochloride   undergoes rapid decay, accelerated and then displayed that provides fast and prevents the elimination of a large amount to get into breast milk. The use of this drug during lactation does not require even a temporary interruption breast-feeding .

Side effects

In the treatment of articaine may experience different side effects affecting the central nervous, digestive and immune systems, the organs of vision. Some patients suffer from headaches and deviations in the normal functioning of the cardiovascular system, such as arrhythmia , Increasing Blood pressure and heart rate .

Perhaps the development of adverse reactions in patients with asthma, for example: disturbances of consciousness . vomiting . diarrhea . attack   asthma . state of shock and   stridor .

Instructions on Ultrakain D-C (method and dosage)

Introduction Ultrakain D-C requires special attention and professionalism, avoids falling into the vessel. Warn intravascular injection also helps test aspiration prior to injection. Not recommended use of the drug in the inflamed tissue sites. Facilitate aspiration can be by using a special syringe for injection By Unidzhekt   and ink cartridges. When this preparation is administered so that the pressure corresponds to the sensitivity of tissue at the injection site.

For each application of the testimony, the expert sets a certain dose of the drug. For example, when preparing a tooth for a crown or a dental cavity for the treatment, using 0, 5-1, 7 ml articaine vestibular for injection, without intervention on the lower premolars. The accuracy of the dose depends on the duration of the intervention and the desired depth of anesthesia. On average, one to conduct dental procedures need 7 mg Articaine hydrochloride   per 1 kg of patient weight.

Overdose

The use of this drug in high doses can cause overdose cases, symptoms of which may include: unexpected dizziness . disturbance of consciousness   and restlessness . It is necessary to urgently stop the introduction of drugs, put the patient in a horizontal position, immediately carry out control of all hemodynamic parameters - pulse, blood pressure and airway. Further treatment is performed depending on manifested symptoms and severity of violations.

Cooperation

The simultaneous use   monoamine oxidase inhibitors   and   tricyclic antidepressants series   articaine with D-C can cause significant vasoconstrictor effect. In addition, the active components of the drug when ingested inhibit human pancreatic secretion of insulin, which helps to reduce the effect of oral hypoglycemic agents.

Also, it does not recommend the use of articaine D-C at the same time beta-adrenoceptor .

The combination with ultrakain Heparin, acetylsalicylic acid and other antithrombotic agents increases the risk of bleeding. Particularly serious bleeding can cause accidental puncture of the vessel wall.

Halothane   and a number of other drugs for inhalation use increase the sensitivity of some of the heart muscle catecholamines Causing arrhythmia .

Terms of sale

Sold by prescription.

Storage conditions

The drug should be stored in a dark, cool and out of reach of children.

Shelf life

2, 5 years.

Analogs

The main counterparts of the drug, also belonging to the group " Local anesthetics "Are:   Ultrakain Dr. C. Forte, articaine D and Trimekain .

Alcohol and articaine D-C

During use of the drug is contraindicated alcohol, as such interaction can cause serious abnormalities in the cardiovascular system and other negative manifestations.

Reviews ultrakain D-C

As a rule, the network found a lot of positive reviews on ultrakain. All patients who were prescribed the drug as an anesthetic during dental procedures, recommend it to other users. They argue that it is the most effective drug that does not cause side effects in this case.

Furthermore, many reports occurs when the anesthetic is used in cosmetics, for example, during the tattooing of the lips. However, some beauty salons client note a strong swelling after such a procedure. Others say that the impact of the drug on them did not particularly affected, but good pain relief.

In any case, before using such drugs, it is necessary to find out how well it transferred. The fact that the development of adverse reactions easier to prevent than to deal with the treatment of negative symptoms.

The difference between articaine D-C and D-C Ultrakain Forte

The French company " Sanofi Aventis "Produces just three possible variations ultrakain, which differ by the presence or absence epinephrine   in its composition and its concentration.

In this way, Ultrakain D-C Forte   It has a concentration of epinephrine 1: 100,000, articaine D-C - the concentration of epinephrine 1: 200,000, and Ultrakain D   It contains no epinephrine without preservatives.

Price ultrakain D-C, where to buy

Injection articaine D-C 40 mg + 5 mg / ml, 10 pcs. You can buy almost any drug store in Russia. The cost of the drug varies between 464-610 rubles.