Description overdue on 12/17/2014
- Latin name: Vitaprost Plus
- ATC code: G04BX
- Active substance: Lomefloksatsin + Prostate extract (Lomefloxacin + Prostate extract)
- Manufacturer: Valium, Open Society (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- candles Vitaprost Plus, instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- Reviews
- Price, where to buy
Composition
The composition of one candle Vitaprost Plus as active ingredients include 100 mg extract the prostate and 400 mg lomefloxacin hydrochloride .
Additional material: fat solid to give suppositories weighing 2.25 grams.
Product form
Rectal suppositories Vitaprost Plus are torpedo-shaped, white or white and brown.
Five of these candles in a contour packaging; One or two such packages in a stack of paper.
Pharmacological action
Candles have Vitaprost Plus anti-inflammatory, antibacterial and prostatotropic action.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Vitaprost Plus - combined with means anti-inflammatory and antibacterial the action of, used at lesions of the prostate gland.
Lomefloksatsin - Antibacterial broad spectrum bactericidal action, refers to the group fluoroquinolones . It acts on the enzyme DNA gyrase of bacteria responsible for the supercoiling DNA It violates the replication and transcription DNA That leads to the death of the bacterial cell.
It has a high activity against aerobic gram-negative microorganisms: Klebsiella pneumoniae, Proteus vulgaris, Neisseria meningitidis, Neisseria gonorrhoeae, Escherichia coli, Citrobacter diversus, Shigella spp., Salmonella spp., Moraxella morganii, Enterobacter cloacae, Pseudomonas aeruginosa, Haemophilus parainfluenzae, Haemophilus influenzae, Legionella pneumophila.
It possesses moderate activity in respect Staphylococcus aureus, Serratia liquifaciens, Staphylococcus epidermidis, Serratia marcescens, Chlamydia trachomatis, Hafnia alvei, Aeromonas hydrophila, Mycobacterium tuberculosis, Citrobacter freundii, Proteus mirabilis, Providencia rettgeri, Proteus stuartii, Providencia alcalifaciens, Enterobacter aerogenes, Klebsiella ozaenae, Klebsiella oxytoca, Enterobacter agglomerans .
Streptococcus spp., Treponema pallidum, Mycoplasma hominis, Ureaplasma urealyticum, Pseudomonas cepacia and anaerobic bacteria are resistant to the drug.
In the vast majority of bacteria lomefloksatsin It acts in small concentrations (usually up to 1 mcg / mL). The development of resistance is detected rarely.
The extract is Prostate Organotropona action on the prostate. Decreases degree edema , Leukocyte infiltration, resulting in the physiological state of the secretory function, increases the amount of lecithin granules, enhances muscle tone of the bladder wall. Hinders thrombus shows antiplatelet Activity prevents thrombosis of venules in the prostate. It normalizes the clinical characteristics and prostate ejaculate. It reduces pain and discomfort, activates the copulatory function.
Pharmacokinetics
No data on the pharmacokinetics of Vitaprost Plus.
Indications
- Acute or chronic prostatitis infectious nature that is caused by sensitive lomefloksatsin by microorganisms, including accompanied by diseases of the genitourinary system of inflammatory character.
- Before and after surgical operations on the prostate gland.
Contraindications
- Age less than 18 years.
- Hypersensitivity the components Vitaprost Plus.
With the utmost care use in patients with epilepsy . cerebral atherosclerosis or other lesions of the nervous system epileptic syndrome .
Side effects
Side effects equipment, except the reactions hypersensitivity , Due to the presence in its composition lomefloxacin .
- The reactions of the nervous system: nervousness, asthenia . dizziness , Anxiety, fatigue, headache . syncope, hallucinations, insomnia, seizures, tremor, hyperkinesia, paresthesia, depression .
- Reaction by the immune system: photosensitization . itch . urticaria, Stevens-Johnson syndrome .
- Reactions on the part of the digestive system: dry mucous membranes of the mouth, pseudomembranous enterocolitis, diarrhea, goiter, constipation Discoloration language, flatulence , Loss of appetite, taste perversion, the activation of hepatic transaminases .
- Reactions on the part of the circulatory system: reduced pressure bradycardia, tachycardia, arrythmia , Worsening of the current congestive heart failure, cardiomyopathy, arrhythmia, pulmonary embolism, phlebitis .
- Reactions on the part of the hematopoietic system: gastrointestinal bleeding, thrombocytopenia , Strengthening of fibrinolysis, purpura, lymphadenopathy , nose bleed.
- Reactions on the part of the genitourinary system: dysuria, glomerulonephritis, polyuria, albuminuria, anuria , Urethral bleeding, urinary retention, hematuria, crystalluria, orchitis, epididymitis.
- Reactions on the part of the musculoskeletal system: vasculitis, arthralgia , Cramping calf muscles, lumbodynia, torakalgiya .
- Reactions from the metabolism: gout, hypoglycemia .
- Reactions on the part of the respiratory system: bronchospasm , Shortness of breath, cough, flu-like symptoms.
- Reactions from the senses: tinnitus, blurred vision.
- Other reactions: sweating, thirst, chills, superinfection.
candles Vitaprost Plus, instructions for use (method and dosage)
Apply rectally, one candle times a day after the enema or defecation. Before using suppository is necessary to to extract from contour packaging. After using the drug the patient is recommended in a horizontal position for 40 minutes.
The duration of treatment is determined by the disappearance of the pathogens in the juice of the prostate and is usually from one to four weeks (determined for each patient individually).
Overdose
Currently there are no reported cases of overdose.
Cooperation
Features of interaction with other drugs have not been studied.
Terms of sale
The drug is available without a prescription.
Storage conditions
- Keep away from children.
- Store in a dark, dry place at temperatures up to 20 degrees.
Shelf life
Two years.
Cautions
During treatment Vitaprost Plus should be limited to the combined use of other fluoroquinolones in order to avoid of overdose and of development of side effects.
During treatment is necessary to avoid prolonged Spent solar to light and application of artificial ultraviolet lighting.
During therapy, patients should be especially careful when driving.
Analogs
Vitaprost Forte
Brusniver
Speman Forte
Speman
Urolesan
Tribestan
Phytolysinum
Kanefron
Gentos
Analogs Vitaprost Plus: Vitaprost, Tutukon, Speman, Vitaprost Forte Gentos, Kanefron H Lespefril, Tribestan, Urokran, cystitis Aurina.
Babies
The drug is banned for use in children.
Reviews Vitaprost Plus
Reviews about the candlelight Vitoprost Plus are characterized by a large number of of complaints on the development of side effects, in peculiarities of of diarrhea, because of what course of treatment accounts for to interrupt. Many of these reviews are from individuals to self-medicate. Therefore, use this drug are advised to strictly prescribed by a doctor.
Price Vitaprost Plus, where to buy
The price of candles Vitaprost Plus №10 in Russia is about 764-1027 rubles, Ukraine, the cost averages 418 hryvnia.