Description overdue on 07/25/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Folibera (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Synonyms
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

The composition of one tablet Folibera includes:

• Folic acid (vitamin B9)   - 400 g;
• cyanocobalamin (vitamin B12)   - 2 mg.

Auxiliary components: magnesium stearate . lactose monohydrate , Karboksikrahmal sodium type A, trisodium citrate, microcrystalline cellulose, maltodextrin Citric acid.

Product form

Round or flat yellow pills in the Valium planimetric records of 28 pieces. Packed in cardboard boxes.

Pharmacological action

Foliber drug helps to overcome metabolic blockade, which is observed in embryos with neural tube defect.

Cyanocobalamin   in this case, it is a key substance in the metabolism of essential the amino acid methionine .

Not enough folic acid   the body breaks DNA synthesis   cells. Folic acid is involved in cell division and the synthesis of nucleic acids.

Pharmacodynamics and pharmacokinetics

Folic acid   rapidly absorbed in the jejunum. Once it is in the process methylation 5-methyltetrahydrofolate. The maximum concentration in serum (Cmax) is achieved after 30 - 60 minutes.

In its turn cyanocobalamin   It interacts with a substance that stimulates blood formation (hematopoiesis) . In this case, Cmax in plasma attained after 8-12 hours.

Folic acid and vitamin B12 are subjected to considerable recycling kishechnopechenochnom tract.

Indications

Prevention vitamin B12 deficiency (cyanocobalamin)   and folic acid .

The drug is intended mainly for women of childbearing age who are planning pregnancy . Application desirable to begin at least one month prior to conception. Then, 1 trimester during pregnancy to stabilize the development of the neural tube in children in the first weeks of life.

Contraindications

Individual hypersensitivity to product ingredients.

Foliber contains 23 mg lactose   in one tablet. On the need to pay attention to patients with malabsorption galactose   and Glucose And deficiency Lactase   or with symptoms galactosemia   (violation of the transformation of galactose to glucose)

Side effects

There is the possibility of an allergic reaction.

Instructions for use Folibera (method and dosage)

The drug is used Foliber 1 tablet once a day before meals.

Overdose

Cases of overdose have been noted.

Cooperation

Should not be used in conjunction with Foliber Methotrexate Because it acts as an antagonist of folic acid, and reduces the rate of chemical reactions enzyme gidrofolatreduktazy .

Use of the drug with antiepileptic hydantoin groups   It inhibits and reduces the action of the latter.

Terms of sale

Foliber drug dispensed as a medicine without issuing a prescription.

Storage conditions

Foliber should be stored in a dry place, limited to children. Storage temperature should not exceed 25 ° C.

Shelf life

The product is fit for two years.

Cautions

The drug does not affect the ability to drive vehicles or operate machinery.

Analogs Folibera

Folibera analogs are complex preparations, including in the folic acid   and B vitamins . It - Alvito . Angiovit . Vetoron . Pikovit   et al. The use of analogues should be coordinated with the attending specialist.

Synonyms

Cyanocobalamin (cyanocobalamin), Folic Acid (folate).

Foliber during pregnancy

This drug is designed to compensate the lack of the human body B vitamins . Basic substances Folibera - folic acid   and cyanocobalamin Are important components in order to maintain the current pregnancy. At deficiency of vitamins, medication is required for a successful impact on the processes of tissue development child. Vitamin deficiencies can lead to neural tube defects In this case, Foliber necessary, as a preventive agent even when planning a pregnancy.

The drug is not just a vitamin, but a complex substance that contains a minimal amount of the daily dose (drug application instructed to Foliber).

Foliber during pregnancy can also stimulate blood supply.

Reviews Folibere

Although a relatively new drug Foliber, he found positive recommendations among physicians. Previously, pregnant women or those who are going to plan conception, just appointed folic acid   or separate injections B12 . Today, we have a comprehensive drug that combines the two components. Disposable daily dose contains sufficient availability of folic acid and vitamin C. In this case, the excluded reception of multiple separate ingredients during the day.

On individual applications related to a change in dosage is necessary to consult with the attending physician. Folibere reviews are positive.

Price Folibera

Price Folibera in Ukraine ranges from 98 to 152 grams. depending on the region.

Price in Moscow this medication varies from 226 to 276 rubles.