Description overdue on 09/25/2014

• Composition
• Product form
• Pharmacological action
• Pharmacokinetics and pharmacodynamics
• Indications
• Contraindications
• Side effects
• Instructions for use Milgamma Compositum (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

The composition of medicines Milgamma Compositum   includes active substances benfotiamine   and pyridoxine hydrochloride . Also in the tablets include additional ingredients: Povidone K, microcrystalline cellulose, carmellose sodium, colloidal silicon dioxide, partial glycerides of higher fatty acids, talc.

Product form

The drug is available as a white round pills lenticular. The blisters fit 15 tablets, embedded in cartons 2 or 4 packaging.

Pharmacological action

Tablets Milgamma Compositum is a complex of B vitamins The active ingredients of the drug - and pyridoxine hydrochloride benfotiamine - facilitate the patient with inflammatory and degenerative diseases of the nerves and musculoskeletal system. Milgamma tablets activates blood flow, improves the nervous system.

Benfotiamine   - A substance that plays an important role in the metabolism of carbohydrates. Pyridoxine   involved in protein metabolism in the body, and is partially involved in the metabolism of fats and carbohydrates. Benfotiamine and pyridoxine in high doses as an analgesic effect due benfotiamine participate in the synthesis of Serotonin . There is also a regenerating effect: under the influence of the drug restored the myelin sheath of nerves.

Pharmacokinetics and pharmacodynamics

Benfotiamine - a fat-soluble derivative Vitamin B1   (thiamine). The body substance is phosphorylated in thiamine triphosphate and thiamine diphosphate, which are biologically active coenzymes. The main part of benfotiamine is absorbed in the duodenum, the rest part - in the small intestine.

Pyridoxine is converted into pyridoxal. This enzyme affects the non-oxidative metabolism of amino acids. It participates in the production of physiologically active amines. Mainly absorbed in the upper digestive tract during passive diffusion.

Both active substance derived mainly via the kidneys. The half-life of blood benfotiamine is 3, 6 hours, the half-life of pyridoxine - 2-5 hours.

Indications

Defines the following indications for use Milgamma Compositum as part of a treatment:

• neuritis ;
• optic neuritis ;
• neuralgia ;
• ganglionitis;
• paresis of the facial nerve;
• plexopathy ;
• polyneuropathy . neuropathy ;
• lumbar ischialgia ;
• radiculopathy .

It is also testimony to the use of this drug have people who regularly suffer from nocturnal seizures (in the first place - the elderly), and muscular-tonic syndromes. From what has assigned a drug, the doctor determined individually.

Contraindications

Medicine Milgamma Compositum can not be applied in such diseases and conditions of the organism:

• chronic form of heart failure (decompensation stage);
• hereditary fructose intolerance character;
• sucrase or isomaltase insufficiency;
• galactose malabsorption or glucose;
• High sensitivity to the drug components.

Side effects

Tablets Milgamma Compositum as injections Milgamma may provoke some side effects that usually occur only in rare cases. The following manifestations:

• hives . itchy skin , Difficulty breathing, angioedema . anaphylactic shock ;
• tachycardia ;
• responses associated with high sensitivity ;
• heavy sweating, acne ;
• g olovnaya pain ;
• nausea .

In marked manifestation of any of these side effects should immediately inform the doctor.

Instructions for use Milgamma Compositum (method and dosage)

Instructions for use Milgamma Compositum provides that when administered pills need to drink plenty of fluid.

If the patient is prescribed pills Milgamma, application instructions includes receiving 1 tablet per day. When acute diseases may increase the dose: 1 tablet three times a day. The dosage of such treatment can be no more than 4 weeks, after which the doctor decides to lower doses, since the reception vitamin B6 in large amounts increases the likelihood of developing neuropathy. In general, the course of therapy lasts no more than two months.

Overdose

In case of overdose of vitamin B6 may be a manifestation of neurotoxic effects. In the treatment with high doses of the vitamin for more than six months may develop neuropathy. In case of overdose there may be sensory polyneuropathy, which is accompanied by ataxia. Taking large doses of the drug can cause a manifestation of convulsions. Overdose with oral benfotiamine is unlikely.

After receiving high doses of pyridoxine, induce vomiting, then take Activated carbon . However, such measures are effective only in the first 30 minutes. In more serious cases, you should immediately consult a specialist.

Cooperation

When treating drugs which contain vitamin B6, may decrease the effectiveness of levodopa.

In simultaneous treatment of pyridoxine antagonist or prolonged use of oral contraceptives, which contain Estrogens , There may be a deficiency of vitamin B6.

When concomitantly with fluorouracil deactivation occurs thiamine.

Terms of sale

The pharmacy Milgamma Compositum sold without a prescription.

Storage conditions

Pills should be stored at a temperature not exceeding 25 ° C, keep away from children.

Shelf life

Shelf life - 5 years.

Cautions

Admission drug has no effect on the level of concentration when driving transport and working with dangerous machinery.

Analogs Milgamma Compositum

Analogs tablets Milgamma Kopozitum - are drugs that are composed of the same components. These drugs are pills and injections Milgamma , and Combilipen . Neyromultivit . Triovite   et al. Price analogues depends on the number of tablets in the package, and other products.

Babies

The medicine is not administered to children due to the lack of clear information on the safety of the drug.

During pregnancy and lactation

During pregnancy   and between feeding breastfeed medicine Milgamma Compositum not assigned.

Reviews Milgamma Compositum

Reviews Milgamma Compositum forums mostly positive. It is noted that the drug helps to get rid of unpleasant symptoms, compulsive neurological pain, seizures. Reviews of pills rarely contain information on the side effects.

Price Milgamma Compositum where to buy

Price Milgamma Compositum tablets 30 pcs. It is from 550 to 650 rubles. Buy in Moscow pills in a package of 60 pieces. It can be as low as 1,000 to 1,200 rubles. Price Milgamma Compositum in St. Petersburg similar. How much are the pills can be found in the specific field of sales. Injections Milgamma worth an average 450 rubles (10 vials).