Description overdue on 05/20/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions on Vitrum Centuria
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

One tablet contains:

• acetate, retinol (vitamin A)   and betakaroten   - 6000 IU (corresponds to the content   retinol acetate and - 2 mg betakarotena   - 112 g);
• alpha-tocopherol acetate (vitamin E)   - 45 IU (45 mg);
• phytomenadione (vitamin K1)   - 10 g;
• cholecalciferol (vitamin D3)   - 400 IU (10 micrograms);
• ascorbic acid (vitamin C)   - 60 mg;
• thiamine hydrochloride (vitamin B1)   - 1.5 mg;
• pyridoxine hydrochloride (vitamin B6)   - 3 mg;
• Riboflavin (vitamin B2)   - 1.7 mg;
• pantothenic acid   (as calcium pantothenate   - Vitamin B5 ) - 10 mg;
• nicotinamide (vitamin PP)   - 20 mg;
• cyanocobalamin (vitamin B12)   - 25 g;
• Folic acid (vitamin B9)   - 200 g;
• calcium ( as calcium hydrogen phosphate ) - 200 mg;
• Biotin (vitamin H)   - 30 g;
• magnesium (as magnesium oxide ) -100 Mg;
• potassium   (as potassium chloride ) - 80 mg;
• phosphorus (as calcium hydrogen phosphate ) - 48 mg;
• copper   (as copper oxide ) - 2 mg;
• iron   (as iron fumarate ) - 9 mg;
• manganese   (as manganese sulfate ) - 2.5 mg;
• zinc   (as zinc oxide ) - 15 mg;
• iodine   (as potassium iodide ) - 150 g;
• selenium   (as   Sodium selenate ) - 20 g;
• boron   (as sodium borate ) - 150 mcg;
• nickel   (as nickel sulfate ) - 5 mcg;
• chrome   (as chromium chloride ) - 100 mcg;
• molybdenum   (as sodium molybdate ) - 25 mg;
• vanadium   (as sodium metavanadate ) - 10 mcg;
• chloride   (as potassium chloride ) - 72 mg;
• silicon (as sodium metasilicate ) - 10 micrograms.

Part Vitrum Centuria Forte   further includes:

• tin   (as tin chloride ) - 5 g;
• lutein   - 100 mcg;
• leaf plants Ginkgo Biloba   in powder - 20 mg.

As auxiliary substances are used: microcrystalline cellulose, stearic acid, colloidal silicon dioxide, croscarmellose sodium, magnesium stearate .

The structure of the shell consists of: hypromellose, triacetin, titanium dioxide Black dye, yellow dye sunset, red dye charming.

Product form

The drug is available in the form of kapsulovidnyh coated tablets film-gray, with a dividing strip on the edge; on the side section - the core of straw color, with dark or light inclusions; possible presence of a specific flavor. The plastic bottles of 30, 60, 100, 120 or 130 such Tablets (for Vitrum Centuria ) In blisters of 30 tablets (for Vitrum centuries Forte ). One such vial or 1, 2, 3 of blisters in a carton box.

Pharmacological action

Fill gaps vitamins   and minerals .

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Vitrum TSentrum refers to the group of medicines called a multivitamin or multivitamin preparations. Composition contains all vitamins and minerals in doses necessary for the elderly after 50 years. Increases resistance to disease, common in this age, increases physical and mental performance. Reduces the risk of cancer and heart disease, prevent premature aging.

• Vitamins A, E, C, beta-carotene, selenium, zinc, copper   and   manganese   are antioxidants protecting cell components, including of chromosome From damage by oxygen radicals.
• Vitamin A   elderly people responsible for T-   and B-cell-mediated immunity As well as to accelerate the synthesis of Cytokine . Retinoic acid   It supports activity of the cells-of killers, playing basic role in antiviral and anticancer Protection of.
• Betakaroten   It is used in the body for constructing the molecules vitamin A It prevents damage to the cell membrane lipid peroxidation products.
• Ascorbic acid   - A powerful antioxidant, increases nonspecific resistance of the organism.
• Vitamin E - Is also a powerful antioxidant, it is used in the biosynthesis Hemoglobin   and proteins that affect the state of the vessels.
• Selenium   It is converted in the body glutadionperoksidazu That protect cells and tissues from organic hydroperoxides.
• Vitamins B1, B2   and   B6   play an important role in normalization of protein, of fat and carbohydrate exchange.
• Vitamin B1   It contributes to the proper functioning of the biochemical processes of the nervous, endocrine and cardiovascular systems.
• Riboflavin   - Component flavin enzymes Providing tissue respiration and the formation of molecules ATP   in cells, as well as numerous high-cost energy redox processes.
• Vitamin B6   involved in the metabolism glycogen . amino acids . sphingoid bases   and products neurotransmitters .
• Nicotinamide   - A component of proteins dehydrogenases carrying hydrogen ions in the cells.
• Pantothenic acid   involved in the process of restoring the endothelium and the exchange of fatty acids.
• Cyanocobalamin   needed for the production of nucleotides, and fatty acid metabolism, passing methylation processes in cells. Together with folic acid plays an important role in the maintenance of hematological and nevrologicheskgo homeostasis.
• Folic acid   CoA molecules is responsible for synthesis and breakdown of amino acids and nucleic acids. Use the required amount of folic acid is the prevention of a number of cancers, particularly cancer of cancer of the colon and rectum, lung, esophagus, stomach.
• Vitamin K1   used for prophylaxis osteoporosis Possesses anti-inflammatory and anti-sclerotic effect, controls the level of glucose in the blood and improves the clinical picture Alzheimer .
• Vitamin D .   copper, calcium, magnesium, manganese, zinc   and boron   play an important role in the prevention of osteoporosis (brittle bones).
• Iodine   - An important component of the hormones Thyroid Supporting the proper functioning of many metabolic processes, maintain immunity.
• Iron   - Part hemoglobin a , Carries oxygen to organs and tissues, and cellular respiration, and many other proteins ( myoglobin flavoproteins, transferrin, lactoferrin, hemosiderin ). It improves appetite, stimulates the processes of reconstruction and recovery.
• Molybdenum   molecules involved in building sulfitokinazy, ksantooksidazy   and aldehyde Responsible for the destruction of certain amino acids   and heterocyclic bases ( purines   and pyrimidine ). These processes affect the body's neurological status.
• Chrome   enhances the effect of insulin .
• Nickel   in special proteins regulate iron metabolism.
• Silicon - Building material for bones and Collagen .

At Vitrum centuries Forte additionally contains:

• Lutein   - Prevent vision loss and improves sharpness;
• leaf powder plant Ginkgo Biloba   - A proven means of boosting cognitive function   (memory score, attention, etc.) in the elderly;
• tin   - It improves recovery processes, regulates the activity flavin enzymes , A component of the molecule gastrin .

Pharmacokinetics

Pharmacokinetics studies have not been conducted.

Indications

Prevention and treatment of vitamin and mineral deficiencies in the elderly, including:

• during mental and physical exertion;
• during the treatment and rehabilitation of an illness;
• unbalanced nutrition.

Contraindications

Hypersensitivity to the drug and its components; hypercalcemia, gipermagniemiya, hypercalciuria, nephrolithiasis,   active tuberculosis   lung sarcoidosis   in anamnesis, hypervitaminosis A, E   and D . thrombophlebitis , Fructose intolerance, gout , Metabolic disorder of copper or iron, severe renal dysfunction, hyperuricemia, erythremia, chronic cardiac insufficiency . thyrotoxicosis . stomach ulcers and 12 duodenal ulcer   (possible increase in acidity), the joint use of retinoids, selenium .

Side effects

• On the part of the immune system: possible reactions hypersensitivity Including anaphylaxis . angioedema , Raise of temperature at persons with Allergies.
• For the skin rash, hives , Redness of the skin, itching.
• From the gastrointestinal tract: nausea, dyspepsia, abdominal pain, belching, diarrhea , Constipation, gastric hyperacidity, heartburn.
• On the part of the central nervous system: dizziness, headache, irritability, drowsiness.

When long-term reception in high doses may occur: irritation of the digestive tract, hypercalcemia, paresthesia, hyperuricemia, hyperglycemia, impaired renal function, a temporary increase in liver enzymes and alkaline phosphatase , Dry skin, seborrheic rash, hair loss.

Instructions on Vitrum Centuria

Instructions for use Vitrum centuries Forte is no different from the instructions on the Vitrum centuries and prescribe oral 1 tablet a day after meal. The course of treatment drug of is 3 months. Prescribed by a doctor may be held refresher courses.

Overdose

No reported cases of overdose. Iron overdose include nausea, diarrhea , By pains in the abdomen, lethargy. Occurrence hyperglycemia and   and acidosis .

Treatment of overdose: gastric lavage, symptomatic therapy.

Cooperation

Since Vitrum centuriae composition contains iron and calcium in the relevant sections of the digestive system may decrease absorbability antibiotics tetracycline group   and fluoroquinolones . Ascorbic acid   enhances the effects of sulfonamides . Antacids Comprising magnesium, aluminum, calcium,   reduce the absorption gland . Iron supplements and silver lower bioavailability Vitamin E . Folic acid activates metabolism phenytoin .

Terms of sale

The drug is available without prescription.

Storage conditions

Store at temperatures up to 30 degrees of the reach of children.

Shelf life

36 months.

Cautions

Caution should be prescribed the drug for liver and kidney, gastric ulcer and 12 duodenal ulcer   in past, diabetes . cholelithiasis . pancreatitis .
The drug should not be prescribed the drug, along with other multivitamin complexes, as there may be an overdose.

Analogs

Analogues of drugs are vitamin complexes close or identical composition: Vitrum Prenatal . Multimaks Kinder . Multimaks Prenatal, Oligovit, Supervit   and others.

Babies

Not recommended for use in children.

During pregnancy and lactation

Investigation of the influence of the drug during pregnancy and lactation has not been, therefore, should refrain from taking the drug in these states.

Reviews of Vitrum Centuria

Reviews of vitamins fixed numerous cases confirm the claimed effect in patients applies Vitrum Centrum after 50 years.

Price Vitrum Centuria

In Russia, the average price Vitrum centuries Forte (30 tablets) is close to 415 rubles, Vitrum Centuria   -380 Rubles; Ukraine 79 and 70 hryvnia respectively.