Description overdue on 20.10.2011

Acyclovir   is a drug with antiviral properties. Especially effective it affects simplex viruses Herpes   and herpes zoster . This drug - analogue purine nucleoside dezoksiguanidina , The normal component of DNA. The drug has a selective effect on the synthesis of viral DNA. Wherein acyclovir triphosphate   It has no effect on the replication of the DNA of human cells.

Absorption of the drug acyclovir when ingestion occurs only about 20%. Because the body after receiving the drug intravenously or through the kidneys into the output after three hours. However, in people with renal failure   such period last up to 19 5 hours.

Indications and methods of use of the drug:

The drug stops the development of acyclovir herpes rash, reduces the likelihood of dissemination of the skin , and visceral complications . When he received a lot faster crusts are formed, and in the period of acute herpes zoster pain weakened.

Intravenous acyclovir is entered when there are infections that causes herpes simplex virus, and thus the patients immune system is compromised. Also, this way the drug is administered in the event of severe primary infections of genitals, provided that the infection is herpes simplex virus infections, and that provokes the virus herpes zoster. Acyclovir is prescribed to patients with severely impaired immune system to prevent infections, which are caused by the herpes virus. PM acts as immunopotentiator .

The drug in tablets prescribed to patients with infections of the skin and mucous membranes, occurrence of which provokes the herpes simplex virus. Also, the drug in the form prescribed for the prevention of disease in patients with impaired immunity and for the treatment of herpes zoster. Adults with the infection that causes herpes simplex virus, one pill five times a day. Prophylactic dose is one tablet four times a day. Patients with shingles take 4 tablets five times a day. Children two years of age can take the entire dose for adults and children under two years of age can take half a dose. As a rule, the treatment lasts for five days, patients with herpes zoster acyclovir take an additional three days after the symptoms disappear. Do not recommend the use of this drug for the treatment of newborns.

Atstklovir can be administered intravenously to adults and children who are twelve years old. The drug is administered at 5 mg / kg three times a day, with shingles patients who observed abnormalities in immunity, administered 10 mg / kg every eight hours. Children from three months to twelve years old receive 5 mg / kg. To prepare a solution formulation for intravenous administration, one vial aciclovir should be diluted in 10 ml of a special solvent or isotonic sodium chloride solution. Such a solution is administered by injection is very slow. Drip applying solution must be further diluted in 50 ml of solvent. Exclusively fresh solutions.

People with impaired kidney function and elderly patients can reduce the dose of the drug. For prophylactic purposes take acyclovir typically for six weeks. Patients with herpes keratitis   prescribe acyclovir ophthalmic ointment. It must lay in the conjunctival sac five times a day for 7-10 days. For infections of the skin and mucous membranes, which causes herpes virus, a drug used in the form of a cream. It is applied to the surface with a lesion up to five times per day. The therapy lasts 5-10 days.

Contraindications and possible side effects:

The drug should not be taken for people with individual intolerance to the components. Ability to take acyclovir during pregnancy and breastfeeding to date has not been investigated. Typically, the drug is well tolerated. Sometimes the side effects you may experience nausea, diarrhea, vomiting, headaches, a manifestation of allergy, severe fatigue. With the introduction of the drug into the vein may increase blood levels of urea, bilirubin, creatinine . It may also increase the activity of liver enzymes. Local reactions occur when dissolved acyclovir gets under the skin.

Specific recommendations:

Store drug acyclovir needed in a dark place under the rules of the list B.